I0460000
Isoleucine
European Pharmacopoeia (EP) Reference Standard
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Synonym(s):
L-Isoleucine, (2S,3S)-2-Amino-3-methylpentanoic acid
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein:
1721792
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
leucine
manufacturer/tradename
EDQM
mp
288 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CC[C@H](C)[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
InChI key
AGPKZVBTJJNPAG-WHFBIAKZSA-N
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Isoleucine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
related product
Product No.
Description
Pricing
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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B J Eikmanns et al.
Antonie van Leeuwenhoek, 64(2), 145-163 (1993-01-01)
The Gram-positive bacterium Corynebacterium glutamicum is used for the industrial production of amino acids, e.g. of L-glutamate and L-lysine. In the last ten years genetic engineering methods were developed for C. glutamicum and consequently, recombinant DNA technology was employed to
Jirí Svoboda et al.
Phytochemistry, 71(13), 1445-1449 (2010-06-24)
Our understanding of plant defensive mechanisms against herbivore and pathogen attack has significantly increased over the past decade. The complex cascade of defensive events is initiated and controlled by a network of interacting plant hormones. Especially, the conjugate of jasmonate
Vijay Joshi et al.
Amino acids, 39(4), 933-947 (2010-02-27)
Pathways regulating threonine, methionine and isoleucine metabolism are very efficiently interconnected in plants. As both threonine and methionine serve as substrates for isoleucine synthesis, their synthesis and catabolism under different developmental and environmental conditions also influence isoleucine availability. Together, methionine
Anna L Vestergaard et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1334-E1343 (2014-04-08)
P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet, upholding an essential membrane asymmetry. The mechanism of flipping this giant substrate has remained an enigma. We have investigated the
Song-Yu Yang et al.
Molecular genetics and metabolism, 92(1-2), 36-42 (2007-07-10)
The HSD17B10 gene maps on chromosome Xp11.2, a region highly associated with X-linked mental retardation. This gene encodes HSD10, a mitochondrial multifunctional enzyme that plays a significant part in the metabolism of neuroactive steroids and the degradation of isoleucine. The
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