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H9026

Sigma-Aldrich

Sodium hexanesulfonate

BioXtra

Synonym(s):

1-Hexanesulfonic acid sodium salt

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About This Item

Linear Formula:
C6H13O3SNa
CAS Number:
2832-45-3
Molecular Weight:
188.22
EC Number:
220-601-3
MDL number:
MFCD00007542
UNSPSC Code:
12161900
PubChem Substance ID:
24895841
NACRES:
NA.21

description

anionic

Quality Level

100

product line

BioXtra

mol wt

188.22 g/mol

technique(s)

HPLC: suitable

impurities

<0.001% Phosphorus (P)
<0.1% Insoluble matter

solubility

H2O: 0.1 M at 20 °C, clear, colorless

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Pb: <0.001%
Zn: <0.0005%

SMILES string

[Na+].CCCCCCS([O-])(=O)=O

InChI

1S/C6H14O3S.Na/c1-2-3-4-5-6-10(7,8)9;/h2-6H2,1H3,(H,7,8,9);/q;+1/p-1

InChI key

QWSZRRAAFHGKCH-UHFFFAOYSA-M

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Application

<ul>
<li><strong>Ion pair assisted micro matrix solid phase dispersion extraction of alkaloids from medical plant</strong>: Sodium hexanesulfonate was used as an ion-pairing reagent in the extraction of alkaloids for pharmacological studies, demonstrating its efficacy in enhancing the selectivity and sensitivity of HPLC methods in the analysis of complex plant matrices (Dong et al., 2020).</li>
<li><strong>Pharmacokinetic Properties of Arsenic Species after Intravenous and Intragastrical Administration of Arsenic Trioxide Solution in Cynomolgus Macaques Using HPLC-ICP-MS</strong>: This study highlights the role of Sodium hexanesulfonate in improving the chromatographic profiles of arsenic species, which is crucial for accurate pharmacokinetic assessment in pharmaceutical research (Shi et al., 2019).</li>
<li><strong>Organic solvent-free reversed-phase ion-pairing liquid chromatography coupled to atomic fluorescence spectrometry for organoarsenic species determination in several matrices</strong>: Sodium hexanesulfonate is utilized as a solvent-free ion-pairing agent, enabling greener analytical processes without compromising the performance of liquid chromatography systems (Monasterio et al., 2011).</li>
</ul>

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Philip Zakaria et al.
Electrophoresis, 23(17), 2821-2832 (2002-09-11)
The separation of a series of aromatic carboxylic acids, sulfonates and opiates using electrokinetic chromatography employing a mixture of the soluble cationic polymer poly(diallydimethylammonium chloride) (PDDAC) and the amphiphilic anion hexanesulfonate as pseudostationary phases is described. In this system, the
Kirti S Niralwad et al.
Ultrasonics sonochemistry, 17(5), 760-763 (2010-03-17)
1-Hexanesulphonic acid sodium salt was found to be an efficient catalyst for the green synthesis of alpha-aminophosphonates by the coupling of aldehydes/ketone, an amine and triethyl phosphite under ultrasound irradiation at ambient temperature for appropriate time to furnish the desired
A R Calhoun et al.
Journal of colloid and interface science, 309(2), 505-510 (2007-03-03)
Measurements have been made to determine the solubility of ethane, C2H6, in aqueous solutions of four different surfactants of the linear alkanesulfonate class at 25 degrees C. The surfactants, sodium 1-pentanesulfonate, sodium 1-hexanesulfonate, sodium 1-heptanesulfonate, and sodium 1-octanesulfonate, all share
Miriam Gochin et al.
Journal of medicinal chemistry, 52(14), 4338-4344 (2009-06-19)
The hydrophobic pocket within the coiled coil domain of HIV-1 gp41 is considered to be a hot-spot suitable for small molecule intervention of fusion, although so far it has yielded only microM inhibitors. Previous peptide studies have identified specific hydrophobic
R Salazar-González et al.
Molecular biology reports, 41(12), 7833-7843 (2014-08-29)
Arylamine N-acetyltransferase 2 (NAT2) metabolizes isoniazid (INH) and Single Nucleotide Polymorphisms (SNP) responsible for its activity has been reported. The aim of this study in the Mexican mestizo population was to evaluate NAT2 expression at the protein level in immune
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