G7651
Glutaraldehyde solution
Grade I, 50% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use
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Synonym(s):
Glutaric dialdehyde solution, Pentane-1,5-dial
Linear Formula:
OHC(CH2)3CHO
CAS Number:
Molecular Weight:
100.12
Beilstein:
605390
MDL number:
UNSPSC Code:
12352114
PubChem Substance ID:
NACRES:
NA.21
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Quality Level
type
Grade I
form
liquid
concentration
50% in H2O
technique(s)
electron microscopy: suitable (fixative)
color
colorless
mp
-21 °C ((-6 °F))
solubility
water: soluble
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(CCCC([H])=O)=O
InChI
1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChI key
SXRSQZLOMIGNAQ-UHFFFAOYSA-N
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General description
Glutaraldehyde is a saturated dialdehyde, which is widely known as a chemical sterilant. Glutaraldehyde solutions comprise both monomers and polymers with a difference in their fixation efficiency.
Application
Glutaraldehyde solution has been used:
- along with 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer to fix the concentrated extracellular vesicles (EVs) on concanavalin A for scanning electron microscope (SEM)
- as a component in a solution to fix the cells to observe its morphology
- to fix the Escherichia coli cells in aqueous solution to preserve the surface morphology of bacterial cells
Biochem/physiol Actions
Glutaraldehyde is applicable in biomedical research to fix cells and can also be used to analyze healthy and pathologic red blood cells.
Features and Benefits
- Highly efficient and safe to use with lensed instruments, rubber, or plastics
- Non-corrosive to metals
- Minimum shelf life of 14 days
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Supplementary Hazards
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Stéphane Jauréguiberry et al.
Blood, 124(2), 167-175 (2014-05-27)
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
Stephanie J Bissel et al.
Journal of neuropathology and experimental neurology, 74(8), 767-777 (2015-06-27)
Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is associated with seizures and destructive periventricular white matter lesions. Despite unremarkable cerebrospinal fluid (CSF), HPeV3 RNA can
Jamie Hinks et al.
Applied and environmental microbiology, 81(6), 1949-1958 (2015-01-13)
The modification of microbial membranes to achieve biotechnological strain improvement with exogenous small molecules, such as oligopolyphenylenevinylene-conjugated oligoelectrolyte (OPV-COE) membrane insertion molecules (MIMs), is an emerging biotechnological field. Little is known about the interactions of OPV-COEs with their target, the
Irene Costantini et al.
Scientific reports, 5, 9808-9808 (2015-05-08)
Extensive mapping of neuronal connections in the central nervous system requires high-throughput µm-scale imaging of large volumes. In recent years, different approaches have been developed to overcome the limitations due to tissue light scattering. These methods are generally developed to
Ming Fang et al.
BMC neuroscience, 16, 84-84 (2015-11-27)
Scutellarin, an anti-inflammatory agent, effectively suppressed microglia activation in rats with middle cerebral artery occlusion (MCAO). Robust microglia activation, acute in onset, was followed by astrogliosis. This study was aimed to determine if scutellarin would also affect the reactive astrocytes
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