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G2039

Sigma-Aldrich

Gentian Violet

meets USP testing specifications

Synonym(s):

Crystal Violet, Basic Violet 3, Gentian Violet, Hexamethylpararosaniline chloride, Methyl Violet 10B

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About This Item

Linear Formula:
C25H30N3Cl
CAS Number:
548-62-9
Molecular Weight:
407.98
Colour Index Number:
42555
Beilstein:
3580948
EC Number:
208-953-6
MDL number:
MFCD00011750
UNSPSC Code:
12352100
PubChem Substance ID:
24895083
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

mp

205 °C (dec.) (lit.)

antibiotic activity spectrum

fungi

application(s)

pharmaceutical (small molecule)

Mode of action

cell membrane | interferes
enzyme | inhibits

SMILES string

[Cl-].CN(C)c1ccc(cc1)\C(c2ccc(cc2)N(C)C)=C3/C=C\C(C=C3)=[N+](/C)C

InChI

1S/C25H30N3.ClH/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6;/h7-18H,1-6H3;1H/q+1;/p-1

InChI key

ZXJXZNDDNMQXFV-UHFFFAOYSA-M

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General description

Gentian Violet, also known as crystal violet, is a synthetic triarylmethane dye. It is widely used in various applications, including histology, microscopy, and microbiology. It is often used to stain tissues, cells, and microorganisms for visualization and identification purposes.

Application

Gentian Violet is the primary stain used in the Gram stain technique for differentiation of Gram-negative versus Gram-postive bacteria. Used as a component of CV cytotoxicity assays.

Signal Word

Danger

Hazard Statements

H302,H318,H351,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of Cu vanadate nanorods for visible-light photocatalytic degradation of gentian violet.
Lin N, et al.
Crystal Research and Technology, 50(3), 255-262 (2015)
New Twist on an Old Favorite: Gentian Violet and Methylene Blue Antibacterial Foams.
Karen Edwards
Advances in wound care, 5(1), 11-18 (2016-02-10)
Betsy N Perry et al.
The Journal of investigative dermatology, 126(10), 2316-2322 (2006-06-03)
Hemangioma of infancy is the most common neoplasm of childhood. While hemangiomas are classic examples of angiogenesis, the angiogenic factors responsible for hemangiomas are not fully understood. Previously, we demonstrated that malignant endothelial tumors arise in the setting of autocrine
Mariana Boiani et al.
Journal of medicinal chemistry, 49(11), 3215-3224 (2006-05-26)
Three series of benzimidazole N-oxide derivatives were developed and were examined for their activity against trypanosomatid parasites (Trypanosoma cruzi and Leishmania spp.). 2H-benzimidazole 1,3-dioxides displayed remarkable in vitro activities against both parasites, with derivatives 28, 29, and 32 being the
Diego Benitez et al.
Journal of medicinal chemistry, 54(10), 3624-3636 (2011-04-22)
For a fourth approach of quinoxaline N,N'-dioxides as anti-trypanosomatid agents against T. cruzi and Leishmania, we found extremely active derivatives. The present study allows us to state the correct requirements for obtaining optimal in vitro anti-T. cruzi activity. Derivatives possessing
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