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Flufenamic acid

analytical standard, for drug analysis

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Synonym(s):
N-(3-[Trifluoromethyl]phenyl)anthranilic acid, N-(α,α,α-Trifluoro-m-tolyl)anthranilic acid
Linear Formula:
2-(CF3C6H4NH)C6H4CO2H
CAS Number:
530-78-9
Molecular Weight:
281.23
EC Number:
208-494-1
MDL number:
MFCD00002422
UNSPSC Code:
41116107
PubChem Substance ID:
329799777
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

132-135 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F

InChI

1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)

InChI key

LPEPZBJOKDYZAD-UHFFFAOYSA-N

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General description

Flufenamic acid, a non-steroidal anti-inflammatory drug, is an effective analgesic agent.

Application

Flufenamic acid has been used as a standard in studying the two well defined, polymorphs of flufenamic acid like form I and form III, using solid-state density functional theory and terahertz spectroscopy.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Conformational origins of polymorphism in two forms of flufenamic acid
Delaney P S, et al.
Journal of Molecular Structure, 1078, 83-89 (2014)
Julia C Schwarz et al.
International journal of pharmaceutics, 437(1-2), 83-88 (2012-08-21)
Nanocarriers are highly interesting delivery systems for the dermal application of drugs. Based on a eudermic alkylpolyglycosid nanoemulsions, solid lipid nanoparticles (SLN) and nano-structured lipid carriers (NLC) were prepared by ultrasonic dispersion. The ultrasound preparation technique turned out to be
Antonella Di Pizio et al.
Cellular and molecular life sciences : CMLS, 77(3), 531-542 (2019-06-27)
Human bitter taste receptors (TAS2Rs) are a subfamily of 25 G protein-coupled receptors that mediate bitter taste perception. TAS2R14 is the most broadly tuned bitter taste receptor, recognizing a range of chemically diverse agonists with micromolar-range potency. The receptor is
Minsoo Kim et al.
Pharmaceutics, 11(3) (2019-03-22)
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-DHPs. This study was designed to evaluate
Jon Andoni Sánchez et al.
Immunobiology, 222(2), 241-250 (2016-10-11)
Previous works with autumnalamide reported that Store Operated Calcium (SOC) channels were blocked through mitochondrial modulation. In the present paper we studied the effect of autumnalamide on ionomycin Ca2+ fluxes. Thus, autumnalamide did not modify ionomycin-sensitive intracellular pools while the
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