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About This Item
Empirical Formula (Hill Notation):
C24H21Cl2N3O4S
CAS Number:
Molecular Weight:
518.41
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
S(c2ccc(cc2)COC(C[n]4cncc4)c3c(cc(cc3)Cl)Cl)c1ccccc1.[N+](=O)([O-])O
InChI
1S/C24H20Cl2N2OS.HNO3/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20;2-1(3)4/h1-14,17,24H,15-16H2;(H,2,3,4)
InChI key
FJNRUWDGCVDXLU-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
fenticonazole
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Fenticonazole nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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F Murina et al.
Minerva ginecologica, 64(2), 89-94 (2012-04-07)
The aim of this paper was to compare the efficacy of fluconazole 150 mg and intra-vaginal fenticonazole 600mg in short-course treatment of the acute episode of vulvovaginal candidiasis (VVC). In a prospective study, 80 patients with clinical and mycological (SavvyCheck™
Srpski arhiv za celokupno lekarstvo, 140(7-8), 469-474 (2012-10-25)
Uncomplicated vulvovaginal candidiasis appears in 75% women of reproductive age. The most frequent causes are Candida albicans (85-95%) or C. glabrata, and infrequently C. krusei, C. tropicalis, C. parapsilosis, C. pseudotropicalis, etc. The aim of the study was to investigate
W Speed et al.
Rapid communications in mass spectrometry : RCM, 9(14), 1452-1456 (1995-01-01)
A method is described for the determination of fenticonazole in human female plasma. The method utilizes high performance liquid chromatography coupled to atmospheric pressure positive-ion chemical ionization triple quadrupole mass spectrometry. Multiple reaction monitoring is employed for selectivity and sensitivity
P Altmeyer et al.
The Journal of international medical research, 18(1), 61-67 (1990-01-01)
A double-blind clinical trial was performed to evaluate efficacy and tolerance of once-daily 2% fenticonazole compared with 1% cyclopyroxolamine spray applied for 2-4 weeks in 100 patients with cutaneous mycotic lesions. After treatment lasting 21.9 +/- 6.7 or 22.5 +/-
A G Lawrence et al.
Current medical research and opinion, 12(2), 114-120 (1990-01-01)
An open, randomized comparative clinical trial was performed in 153 patients suffering from symptomatic vaginal candidiasis confirmed by mycological tests. Patients were allocated at random into two groups: the first group (consisting of 75 subjects) was treated with a single
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