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About This Item
Empirical Formula (Hill Notation):
C17H15ClO4
CAS Number:
Molecular Weight:
318.75
Beilstein:
2058973
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
fenofibrate
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2
InChI
1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
InChI key
MQOBSOSZFYZQOK-UHFFFAOYSA-N
Gene Information
human ... PPARA(5465)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Fenofibrate impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured human blood mononuclear cells by procetofenic acid.
C Massaroli et al.
Pharmacological research communications, 14(1), 51-60 (1982-01-01)
Rapid determination of procetofenic acid in plasma by high-performance liquid chromatography.
M C Caturla et al.
Journal of chromatography, 227(1), 219-222 (1982-01-08)
Simple and rapid method for determining procetofenic acid, an active metabolite of procetofen, in biological fluids by solid-phase extraction and high-performance liquid chromatography.
A C Ramusino et al.
Journal of chromatography, 383(2), 419-424 (1986-12-19)
R Aldini et al.
British journal of pharmacology, 74(3), 611-617 (1981-11-01)
1 Hypolipidaemic agents may increase biliary cholesterol in man, inducing a supersaturated bile. 2 To evaluate this possible side-effect, we have studied bile lipid secretion over a period of 8 h with intact enterohepatic circulation and 4 h with complete
S Pourbaix et al.
Biochemical pharmacology, 33(22), 3661-3666 (1984-11-15)
Hamsters were given a diet containing fenofibrate (0.5% or 0.05%) or its metabolite, LF 2151 (0.15% or 0.015%) or a standard diet for a 3-week period. At the end of this period, the analysis of plasma lipids showed that the
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