ERMDA471IFCC
Human serum (cystatin C)
ERM®, certified reference material
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UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
certified reference material
Agency
ERM®
manufacturer/tradename
JRC
application(s)
clinical testing
format
matrix material
storage temp.
−70°C
General description
Certified for cystatin C in human serum.
ERM-DA471IFCC_cert
ERM-DA471IFCC_report
ERM-DA471IFCC_origin
ERM-DA471IFCC_cert
ERM-DA471IFCC_report
ERM-DA471IFCC_origin
Application
- Serum biomarker for sarcopenia: A study utilized the serum creatinine/cystatin C ratio as a biomarker for sarcopenia components among different age groups in older ndividuals, underscoring the role of human serum cystatin C in monitoring muscle health and potentially guiding interventions (Fang et al., 2024).
- Screening of sarcopenia: The investigation demonstrated the efficacy of using serum creatinine-cystatin C based screenings for sarcopenia in community-dwelling older adults, highlighting cystatin C′s significance as a reliable indicator of muscle degradation, which is crucial for early intervention (Matsuzawa et al., 2024).
- Predictive tool in chronic kidney disease: Research emphasized native T1-mapping combined with human serum cystatin C levels as predictors of renal function decline in chronic kidney disease patients, illustrating cystatin Cs utility in enhancing the diagnosis and management of kidney disease (Shi et al., 2024).
Analysis Note
For more information please see:
ERMDA471/IFCC
ERMDA471/IFCC
Legal Information
ERM is a registered trademark of European Commission
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Aquatic Chronic 3
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
高风险级别生物产品--人源产品
Certificates of Analysis (COA)
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Determination of Cystatin C in human serum by isotope dilution mass spectrometry using mass overlapping peptides.
Gonzalez-Antu?a A, et al.
Journal of Proteomics, 112, 141-155 (2015)
Lynell W Klassen et al.
Biochemical pharmacology, 76(3), 426-436 (2008-07-05)
Alcohol abuse results in liver injury, but investigations into the mechanism(s) for this injury have been hampered by the lack of appropriate in vitro culture models in which to conduct in depth and specific studies. In order to overcome these
Xiao-Li Huang et al.
Clinical and vaccine immunology : CVI, 16(10), 1504-1516 (2009-08-21)
Human immunodeficiency virus type 1 (HIV-1)-specific T-cell reactivity has been related to protection from disease progression. Optimal T-cell reactivity to HIV-1 presumably requires antigen processing and presentation by professional antigen-presenting cells, particularly dendritic cells (DC). Here we examined whether multiple
K Habiro et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 9(6), 1324-1329 (2009-05-23)
Thymus xenotransplantation has been shown to induce tolerance to porcine xenografts in mice and to permit survival of alpha1,3Gal-transferase knockout porcine kidney xenografts for months in nonhuman primates. We evaluated the ability of porcine thymus xenotransplantation to induce human T-cell
Bin Ma et al.
Scientific reports, 1, 140-140 (2012-02-23)
Transport of mRNAs to diverse neuronal locations via RNA granules serves an important function in regulating protein synthesis within restricted sub-cellular domains. We recently detected the Huntington's disease protein huntingtin (Htt) in dendritic RNA granules; however, the functional significance of
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