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E6133

Sigma-Aldrich

Ethanolamine hydrochloride

≥99.0%

Synonym(s):

mea hydrochloride, monoethanolamine hydrochloride, 2-Aminoethanol hydrochloride

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100 G
CN¥1,422.25

CN¥1,422.25

Available to ship onApril 25, 2025Details

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100 G
CN¥1,422.25

About This Item

Linear Formula:
H2NCH2CH2OH · HCl
CAS Number:
2002-24-6
Molecular Weight:
97.54
Beilstein:
3542892
EC Number:
217-900-6
MDL number:
MFCD00012892
UNSPSC Code:
12161700
PubChem Substance ID:
57654165
NACRES:
NA.25

CN¥1,422.25

Available to ship onApril 25, 2025Details

Request a Bulk Order

Quality Level

300

Assay

≥99.0%

form

powder or crystals

storage condition

dry at room temperature

technique(s)

HPLC: suitable

color

white

pH

9—10

pKa (25 °C)

9.5

mp

82-84 °C (lit.)

solubility

water: 0.33 g/mL, clear, colorless to very faintly yellow

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This Item
606308T1502398136
Ethanolamine hydrochloride ≥99.0%

E6133

Ethanolamine hydrochloride

Ethanolamine-13C2 hydrochloride 99 atom % 13C, 99% (CP)

606308

Ethanolamine-13C2 hydrochloride

Triethanolamine hydrochloride ≥99.5% (titration)

T1502

Triethanolamine hydrochloride

Ethanolamine ACS reagent, ≥99.0%

398136

Ethanolamine

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

-

assay

≥99.0%

assay

99% (CP)

assay

≥99.5% (titration)

assay

≥99.0%

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

200

application(s)

general analytical
life science and biopharma
pharmaceutical

application(s)

-

application(s)

diagnostic assay manufacturing

application(s)

-

form

powder or crystals

form

solid

form

crystalline powder

form

liquid

solubility

water: 0.33 g/mL, clear, colorless to very faintly yellow

solubility

-

solubility

water: 0.333 g/mL, clear, colorless

solubility

water: miscible 1000 g/L at 20 °C

General description

Ethanolamine hydrochloride, a versatile compound in biochemistry and molecular biology, plays a pivotal role in diverse research areas. Primarily, it functions as a buffering agent, ensuring a stable pH environment crucial for enzymatic reactions, protein solubilization, and other biological processes. Its significance extends to membrane protein studies, aiding in the extraction of these proteins from cell membranes. It also finds utility in cell culture and as a reagent for biological sample preparation, simplifying nucleic acid and protein isolation, as well as facilitating the detection of proteins by western blotting and immunohistochemistry. This compound′s wide-ranging applications make it indispensable in biochemical research, contributing to various experimental procedures and advancing our understanding in fields such as molecular biology, immunology, and cellular biology.

Application

Ethanolamine hydrochloride has been used:
  • in overnight incubation of the tips to attach primary amine groups at the tip surface[1]
  • in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors[2]
  • to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process[3]
  • in a study as a reagent to study molecular interactions and adhesion forces in biological systems using Atomic Force Microscopy[4]
  • to prepare the reagent for surface-enhanced laser desorption ionization analysis, aimed at studying the role of Interleukins[5]

Biochem/physiol Actions

Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically.[6] It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane.[7] Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia.[6] Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.[8]

Features and Benefits

  • Suitable for Immunology, Cellular Biology and Biochemical Research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Effective Buffering Agent with a pKa of 9.5 (25 °C)

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    The role of interleukin-6 (IL-6) in human sulfur mustard (HD) toxicology
    Arroyo C M, et al.
    International Journal of Toxicology, 20, 281-296 (2001)
    Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth
    Mendoza N, et al.
    Cancer Research, 63(5), 1020-1024 (2003)
    Amino Alcohols-Advances in Research and Application, 29-29 (2013)
    Foodborne Diseases: New Insights for the Healthcare Professional, 14-14 (2012)
    K C Andree et al.
    Lab on a chip, 19(6), 1006-1012 (2019-02-15)
    The load of circulating tumor cells (CTC) is related to poor outcomes in cancer patients. A sufficient number of these cells would enable a full characterization of the cancer. An approach to probe larger blood volumes, allowing for the detection
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