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Merck
CN

E2451000

Etilefrine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Ethylamino-1-(3-hydroxyphenyl)-1-ethanol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H15NO2 · HCl
CAS Number:
943-17-9
Molecular Weight:
217.69
MDL number:
MFCD00060167
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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SMILES string

[Cl-].[N+H2](CC(O)c1cc(ccc1)O)CC, Cl.OC1=CC=CC(=C1)C(O)CNCC

InChI

InChI=1S/C10H15NO2.ClH/c1-2-11-7-10(13)8-4-3-5-9(12)6-8;/h3-6,10-13H,2,7H2,1H3;1H

InChI key

KTNROWWHOBZQGK-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

etilefrine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Etilefrine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H412

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Iheanyi Okpala
Expert opinion on investigational drugs, 15(8), 833-842 (2006-07-25)
Developments in the treatment of sickle cell disease (SCD) have not kept pace with advances in understanding the pathophysiology of this haemoglobinopathy. Drugs undergoing preclinical and clinical assessment for the therapy of these globin gene disorders are discussed in this
C Schwerk et al.
Klinische Padiatrie, 221(2), 93-96 (2009-02-10)
We report here on a case of etilefrinhydrochloride tablet intoxication in suicidal intention in a female adolescent. Tablet ingestion resulted in the formation of a tablet conglomerate in the stomach, which could neither be effectively treated with activated charcoal nor
Ioannis E Platis et al.
Thoracic surgery clinics, 16(3), 209-214 (2006-09-29)
Chylothorax is a rare complication of pulmonary resection. It requires prompt treatment, which is initially conservative. This treatment consists of drainage, nutritional support, and measures to diminish chyle flow. Surgical intervention is indicated when conservative management is ineffective. Delay in
Management of thoracic duct injuries after oesophagectomy (Br J Surg 2001: 88: 1442-8). Letter 1.
P Guillem et al.
The British journal of surgery, 89(6), 809-809 (2002-05-25)
A Muneer et al.
International journal of clinical practice, 62(8), 1265-1270 (2008-05-16)
Priapism is a urological emergency which is commonly classified into low-flow and high-flow priapism. Immediate intervention is required for low-flow cases as the development of ischaemia ultimately leads to long-term erectile dysfunction. Stuttering or recurrent priapism is less well understood.
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