Skip to Content
Merck
CN
All Photos(1)

Documents

D8189

Sigma-Aldrich

Bis(1,3-dibutylbarbituric acid) trimethine oxonol

≥95% purity (HPLC), powder or solid

Sign Into View Organizational & Contract Pricing

Synonym(s):
DiBAC4(3)
Empirical Formula (Hill Notation):
C27H40N4O6
CAS Number:
Molecular Weight:
516.63
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

≥95% (HPLC)

form

powder or solid

color

orange

solubility

DMF: soluble
DMSO: soluble

ε (extinction coefficient)

≥90000 at 490-496 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCCCN(C(N(CCCC)C1=O)=O)C(C1=C/C=C/C2C(N(CCCC)C(N(CCCC)C2=O)=O)=O)=O

InChI

1S/C27H40N4O6/c1-5-9-16-28-22(32)20(23(33)29(26(28)36)17-10-6-2)14-13-15-21-24(34)30(18-11-7-3)27(37)31(25(21)35)19-12-8-4/h13-15,20H,5-12,16-19H2,1-4H3/b14-13+

InChI key

ATJCYSYHWGQAET-BUHFOSPRSA-N

Application

Bis(1,3-dibutylbarbituric acid) trimethine oxonol has been used for monitoring changes in the plasma membrane potential. It also has applications in high throughput screening.
Application in high throughput screening.

Biochem/physiol Actions

Bis(1,3-dibutylbarbituric acid) trimethine oxonolis a translational membrane potential dye that is redistributed in the cell as membrane potential changes.
Translational membrane potential dye that is redistributed in the cell as membrane potential changes.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

B Lee et al.
Journal of applied microbiology, 127(3), 701-712 (2019-06-20)
Metal nanoparticles are promising materials for the management of infectious diseases as known to have various antimicrobial activities in pathogenic micro-organisms. Among them, gold nanoparticles (AuNPs) are used in a wide range of fields such as photodynamic therapy, molecular diagnostics
T Bräuner et al.
Biochimica et biophysica acta, 771(2), 208-216 (1984-04-11)
The usefulness of a new voltage-sensitive fluorescent dye, the membrane permeant negatively charged oxonol dye diBA-C4-(3)-, was evaluated by measuring the membrane potentials of BICR/M1R-k and L cells with glass microelectrodes and simultaneously recording the fluorescence of the stained cells.
Autocrine regulation of glioma cell proliferation via pHe-sensitive K(+) channels.
Honasoge A, et al.
American Journal of Physiology. Cell Physiology, 306, C493-C505 (2014)
Johannes Kassmannhuber et al.
Bioengineered, 8(5), 488-500 (2017-01-26)
In a concept study the ability to induce heterogeneous ice formation by Bacterial Ghosts (BGs) from Escherichia coli carrying ice nucleation protein InaZ from Pseudomonas syringae in their outer membrane was investigated by a droplet-freezing assay of ultra-pure water. As
Nicola Bernabò et al.
Scientific reports, 9(1), 8155-8155 (2019-06-01)
Graphene Oxide (GO) is a widely used biomaterial with an amazing variety of applications in biology and medicine. Recently, we reported the ability of GO to improve the in vitro fertilization (IVF) outcomes in swine, a validated animal model with

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service