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Safety Information

D186309

Sigma-Aldrich

Dimethyl sulfate

≥99.5%

Synonym(s):

Sulfuric acid dimethyl ester

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18 L
CN¥20,587.09

CN¥20,587.09

Estimated to ship onJune 23, 2025Details

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18 L
CN¥20,587.09

About This Item

Linear Formula:
(CH3O)2SO2
CAS Number:
77-78-1
Molecular Weight:
126.13
Beilstein:
635994
EC Number:
201-058-1
MDL number:
MFCD00008416
UNSPSC Code:
12352100
PubChem Substance ID:
57654074
NACRES:
NA.21

CN¥20,587.09

Estimated to ship onJune 23, 2025Details

Request a Bulk Order

vapor density

4.3 (vs air)

Quality Level

200

vapor pressure

0.7 mmHg ( 25 °C)

Assay

≥99.5%

form

liquid

autoignition temp.

923 °F

refractive index

n20/D 1.386 (lit.)

bp

188 °C (lit.)

mp

−32 °C (lit.)

density

1.333 g/mL at 25 °C (lit.)

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This Item
32029341620803071
Dimethyl sulfate ≥99.5%

D186309

Dimethyl sulfate

Dimethyl sulfate ≥99%

320293

Dimethyl sulfate

Dimethyl sulfate purum, ≥95.0% (GC)

41620

Dimethyl sulfate

Dimethyl sulfate for synthesis

803071

Dimethyl sulfate

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

bp

188 °C (lit.)

bp

188 °C (lit.)

bp

188 °C (lit.)

bp

188.5 °C/1013 hPa (decomposition)

mp

−32 °C (lit.)

mp

−32 °C (lit.)

mp

−32 °C (lit.)

mp

-31.8 °C

form

liquid

form

liquid

form

-

form

liquid

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.), n20/D 1.387

refractive index

-

Application

Dimethyl sulfate may be used along with alumina for preparation of monomethylated derivatives of alcohols, phenols and carboxylic acids.[1] It may also be used in combination with dimethylformamide (DMF) to form methoxy-methylene-N,N-dimethyliminium salt, that can be utilized for the preparation of β-lactams.[2]

Packaging

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18 L in Kilo-Lab® packaging not available in all areas.
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Legal Information

Kilo-Lab is a registered trademark of Merck KGaA, Darmstadt, Germany

replaced by

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

181.4 °F - closed cup

Flash Point(C)

83 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    SHBS0779
    SHBR4115
    SHBP3232
    SHBQ0585
    SHBP9161

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    A new method for sequencing DNA.
    Maxam AM and Gilbert W.
    Proceedings of the National Academy of Sciences of the USA, 74(2), 560-564 (1977)
    Chad M Kurylo et al.
    Cell reports, 25(1), 236-248 (2018-10-04)
    Prevailing dogma holds that ribosomes are uniform in composition and function. Here, we show that nutrient limitation-induced stress in E. coli changes the relative expression of rDNA operons to alter the rRNA composition within the actively translating ribosome pool. The most
    Methylation of alcohols, phenols, and carboxylic acids, and selective monomethylation of diols and dicarboxylic acids with dimethyl sulfate by use of alumina.
    Ogawa H, et al.
    Bulletin of the Chemical Society of Japan, 59(8), 2481-2483 (1986)
    DMF-dimethyl sulfate as a new reagent for the synthesis of β-lactams.
    Jarrahpour A and Zarei M.
    Tetrahedron Letters, 50(14), 1568-1570 (2009)
    Kwang Sun Ryu et al.
    The journal of physical chemistry. B, 111(4), 731-739 (2007-01-26)
    The physical properties of polyaniline (PAn) powder, doped by nucleophilic doping of dimethyl sulfate (DMS), were characterized, as well as its electrochemical behaviors, to investigate the possibility of a power source device adopting the PAn-DMS electrodes. It is shown that
    View All Related Papers

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