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D1050000

Dicloxacillin sodium

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Dicloxacillin sodium salt monohydrate
Empirical Formula (Hill Notation):
C19H16Cl2N3NaO5S·H2O
CAS Number:
13412-64-1
Molecular Weight:
510.32
MDL number:
MFCD00167147
UNSPSC Code:
41116107
PubChem Substance ID:
329798665
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dicloxacillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

SMILES string

O.[Na+].Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)-c4c(Cl)cccc4Cl

InChI

1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

SIGZQNJITOWQEF-VICXVTCVSA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dicloxacillin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H334,H335

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Madhura V Dhoka et al.
Journal of AOAC International, 93(2), 531-535 (2010-05-20)
A simple, precise, accurate, and sensitive RP-HPLC method for simultaneous determination of cefixime trihydrate and dicloxacillin sodium in combined tablet dosage form was developed and validated. Chromatographic separation of the two drugs was performed on a Purospher BDS C18 column
Spectro-and Electroanalytical Studies of Interaction of Dicloxacillin Sodium with Copper Acetate.
Kumar T N, et al.
Materials Today, 4(11), 12255-12260 (2017)
Lars Söderberg et al.
International journal of pharmaceutics, 484(1-2), 246-251 (2015-02-25)
Local irritation and inflammation at the site of administration are a common side effect following administration of parenteral formulations. Biological effects of surface (interfacial) activity in solutions are less well investigated than effects caused by other physico-chemical parameters such as

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