Skip to Content
Merck
CN
All Photos(1)

Documents

D0100000

Dapsone

European Pharmacopoeia (EP) Reference Standard

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
4-Aminophenyl sulfone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, Bis(4-aminophenyl) sulfone, DDS, Dapsone
Linear Formula:
(H2NC6H4)2SO2
CAS Number:
80-08-0
Molecular Weight:
248.30
Beilstein:
788055
MDL number:
MFCD00007887
UNSPSC Code:
41116107
PubChem Substance ID:
329798581
NACRES:
NA.24

grade

pharmaceutical primary standard

Agency

EP Reference Standard

API family

dapsone

manufacturer/tradename

EDQM

mp

175-177 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2

InChI

1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChI key

MQJKPEGWNLWLTK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dapsone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Statements

H302,H360F,H371,H373,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 1B - STOT RE 2 - STOT SE 2

Target Organs

Blood, Blood,spleen,Liver

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R E Kast et al.
British journal of neurosurgery, 26(6), 813-817 (2012-05-04)
Lopez-Gomez et al. recently published remarkable but mechanistically unexplained empirical evidence that the old antibiotic dapsone has antiepileptic activity. We addressed the question "Why should a sulfone antibiotic reduce seizures?". We report here our conclusions based on data from past
Hakan M Gürcan et al.
American journal of clinical dermatology, 10(6), 383-396 (2009-10-15)
Dapsone is a chemotherapeutic agent primarily used in treating leprosy, Pneumocystis jiroveci (previously carinii) pneumonia, and malaria. It is also used as an adjuvant in the treatment of pemphigus and pemphigoid. To assess the role of dapsone in the treatment
Noah Scheinfeld
Current opinion in investigational drugs (London, England : 2000), 10(5), 474-481 (2009-05-12)
Allergen Inc has launched Aczone, a topical gel formulation of the antibacterial, anti-inflammatory agent dapsone, for the potential treatment of acne vulgaris. Oral dapsone has demonstrated efficacy in acne, but was associated with severe side effects such as anemia, which
Richard E Kast et al.
Anti-cancer agents in medicinal chemistry, 11(8), 756-761 (2011-06-29)
Data from past research is presented showing that neutrophils are active participants in new vessel formation in normal physiology, in proliferating human endometrium, in non-cancer pathologies as in the pannus of rheumatoid arthritis, and in various cancers, among them glioblastoma.
Amanda Pickert et al.
Expert opinion on pharmacotherapy, 10(9), 1515-1521 (2009-06-10)
Oral dapsone has been available for over 60 years. Its first clinical use was discovered in 1945, when it was found to be efficacious in inhibiting the progression of leprosy. The combined antibacterial and anti-inflammatory pharmacologic activities of dapsone have
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service