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Key Documents

C9481

Sigma-Aldrich

Carboxymethylcellulose sodium

meets USP testing specifications, Medium viscosity

Synonym(s):

Carboxymethylcellulose sodium salt, Sodium carboxymethylcellulose

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.21

Pricing and availability is not currently available.

Agency

USP/NF
meets USP testing specifications

Quality Level

Assay

6.5-9.5% anhydrous basis (Sodium)

form

powder

color

light yellow

pH

(10 g/L68 °F neutral)

viscosity

400-800 cP, 2 % in H2O(25 °C)(lit.)

mp

> 300.05  °C ((> 572.09 °F ))

solubility

water: soluble

SMILES string

[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C

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This Item
132369132381132383
packaging

pkg of 25 Anaerocult P and 25 special incubation bags

packaging

pkg of 25 Anaerocult A mini and 25 special incubation bags

packaging

pkg of 10 Anaerocult A

packaging

pack of 25 bags

storage condition

(Store dry and tightly closed.

Keep in a well-ventilated place.)

storage condition

(Store dry and tightly closed)

storage condition

(Store dry and tightly closed.

Keep in a well-ventilated place.)

storage condition

(Store dry and tightly closed.

Keep in a well-ventilated place.)

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

form

solid

form

solid

form

solid

form

solid

feature

Creates an oxygen free (anaerobic) environment and a CO2 atmosphere in a single petri dish.

feature

Chemically bind oxygen quickly and completely, Creates an oxygen free (anaerobic) environment and a CO2 atmosphere.

feature

Creates an oxygen free (anaerobic) environment and a CO2 atmosphere in a 2.5L anaerobic jar.

feature

Generates an oxygen depleted and CO2-enriched atmosphere in a 2.5 liter anaerobe jar.

General description

Carboxymethylcellulose sodium is a viscous polysaccharide that belongs to a high molecular weight category. It has mucoadhesive property and is used during eye surgery. Carboxymethylcellulose sodium promotes re-epithelialization of the epithelial cells in corneal wounds.[1] It is useful for the study of attached cell and three-dimensional tissue culture models.[2]

Application

Carboxymethylcellulose sodium has been used as a vehicle for tamoxifen citrate,[3] sorafenib,[4] and savolitinib.[5] It has also been used as a component of serum-free medium (SFM) for the suspension of human umbilical vein endothelial spheroids.[6]
Useful for the study of attached cell and three-dimensional tissue culture models.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
    Xu J, et al.
    Clinical Cancer Research, 23(15), 4482-4492 (2017)
    Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
    Simoes BM, et al.
    Testing, 12(12), 1968-1977 (2015)
    The MET inhibitor AZD6094 (Savolitinib, HMPL-504) induces regression in papillary renal cell carcinoma patient-derived xenograft models
    Schuller AG, et al.
    Clinical Cancer Research, 21(12), 2811-2819 (2015)
    Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing
    Garrett Q, et al.
    Investigative Ophthalmology & Visual Science, 48(4), 1559-1567 (2007)
    Swathi Veeroju et al.
    PloS one, 15(6), e0234872-e0234872 (2020-06-20)
    The leading cause of death in Pulmonary Arterial Hypertension (PAH) is right ventricular (RV) failure. The tumor suppressor p53 has been associated with left ventricular hypertrophy (LVH) and remodeling but its role in RV hypertrophy (RVH) is unclear. The purpose

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