Skip to Content
Merck
CN
All Photos(4)

Documents

C6852

Sigma-Aldrich

L-Cysteine hydrochloride monohydrate

98.5-101.0% dry basis, suitable for cell culture, non-animal source, meets EP, USP testing specifications

Sign Into View Organizational & Contract Pricing
All Photos(4)
Synonym(s):
L-Cysteine hydrochloride hydrate (1:1:1)
Linear Formula:
HSCH2CH(NH2)COOH · HCl · H2O
CAS Number:
7048-04-6
Molecular Weight:
175.63
Beilstein:
5158059
EC Number:
200-157-7
MDL number:
MFCD00065606
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24892902
NACRES:
NA.26

biological source

non-animal source

Quality Level

300

Agency

meets EP testing specifications
meets USP testing specifications

Assay

98.5-101.0% dry basis

form

powder or crystals

optical activity

[α]20/D 6.1 to 7.8°, c = 8 in 1 M HCl
[α]25/D 5.7 to 6.8°, c = 8 in HCl (6 N)

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

solubility

water: 1 g/10 mL, clear, colorless

cation traces

Fe: ≤10 ppm
NH4+: ≤0.02%

application(s)

pharmaceutical (small molecule)

functional group

(sulfhydryl)

storage temp.

room temp

SMILES string

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

InChI key

QIJRTFXNRTXDIP-JIZZDEOASA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

L-Cysteine hydrochloride, commonly referred to as Cysteine HCl, is a vital component in biochemical research due to its versatile roles. Derived from the naturally occurring amino acid L-cysteine, this compound plays a crucial part in redox reactions, protein structure, cell culture, and antioxidant activity. Cysteine HCl functions as a reducing agent and a nucleophile in redox reactions. Additionally, it serves as a precursor to glutathione, a potent cellular antioxidant. Its significance extends to protein structure, where it contributes to the formation of disulfide bonds that stabilize protein structures. Cysteine HCl also supports cell growth and viability in cell culture applications. Its widespread applications encompass diverse areas of biochemical research, including redox biology, protein biochemistry, cell biology, and antioxidant investigations.

Application

L-Cysteine hydrochloride monohydrate has been used as a component of yeast dropout media for culturing yeasts. It has also been used as a component of differential reinforced clostridial broth (DRCM) for the isolation of clostridia.

Biochem/physiol Actions

Cysteine (Cys) is a sulfur-containing amino acid that modulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and in involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.
NMDA glutamatergic receptor antagonist.

Features and Benefits

  • Suitable for Cell Culture and Biochemical research
  • High-quality compound suitable for multiple research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.
Description
Pricing

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Protocol for the selection of single-domain antibody
fragments by third generation intracellular
antibody capture
Tomoyuki Tanaka & Terence H Rabbitts
Nature (2009)
Salma Alavi et al.
STAR protocols, 1(3), 100200-100200 (2020-12-31)
The gut microbiome plays an important role in the exclusion of pathogens and, thus, infection outcomes. Microbiome-pathogen interaction studies are complicated by a lack of tractable animal models and differences in animal model versus human microbiomes. We have adapted the
Richard S. Lord, J. Alexander Bralley
Laboratory Evaluations for Integrative and Functional Medicine (2008)
Durga P Neupane et al.
PLoS pathogens, 18(8), e1010731-e1010731 (2022-08-13)
Children are particularly susceptible to typhoid fever caused by the bacterial pathogen Salmonella Typhi. Typhoid fever is prevalent in developing countries where diets can be less well-balanced. Here, using a murine model, we investigated the role of the macronutrient composition
Hui Zhang et al.
eLife, 10 (2021-12-14)
Multidimensional landscapes of regulatory genes in neuronal phenotypes at whole-brain levels in the vertebrate remain elusive. We generated single-cell transcriptomes of ~67,000 region- and neurotransmitter/neuromodulator-identifiable cells from larval zebrafish brains. Hierarchical clustering based on effector gene profiles ('terminal features') distinguished
View All Related Papers

Articles

L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service