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Merck
CN

C1915

Chloropyramine hydrochloride

analytical standard, for drug analysis

Synonym(s):

N-p-Chlorobenzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C16H20ClN3 · HCl
CAS Number:
6170-42-9
Molecular Weight:
326.26
NACRES:
NA.24
PubChem Substance ID:
329774916
UNSPSC Code:
41116107
EC Number:
228-216-2
MDL number:
MFCD00079009

Key Documents

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Product Name

Chloropyramine hydrochloride, analytical standard, for drug analysis

InChI key

VEYWWAGBHABATA-UHFFFAOYSA-N

InChI

1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

SMILES string

Cl.CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
018F0645V
018F0645

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[Application of aqueous Eudragit dispersions to the preparation of controlled release oral antihistamine dosage forms].
A Dévay et al.
Acta pharmaceutica Hungarica, 58(4), 166-172 (1988-07-01)
M Budihna et al.
Pflugers Archiv : European journal of physiology, 431(6 Suppl 2), R217-R218 (1996-01-01)
In isolated rat hearts effects of chloropyramine (CP), histamine H1 antagonist, and famotidine (FA), H2 antagonist, upon two different myocardial injuries, ischaemia-reperfusion and hypoxia-reoxygenation were studied. In both types of injury the effects of drugs were seen mainly during reperfusion
D B Beleslin et al.
Neuropharmacology, 26(8), 1157-1165 (1987-08-01)
The emetic action of noradrenaline was investigated in unanesthetized cats, after it was injected into the cerebral ventricles through chronically implanted cannulae. Intracerebroventricular injection of noradrenaline produced dose-dependent and shortlasting emesis, which was abolished after ablation of the area postrema.
[Toxico-allergic form of erythema multiforme exudativum caused by suprastin].
S M Fedorov et al.
Vestnik dermatologii i venerologii, (9)(9), 50-51 (1986-01-01)
S Sipka et al.
International archives of allergy and immunology, 97(1), 89-92 (1992-01-01)
Using human platelet-rich plasma (PRP) we found that histamine concentration-dependently potentiated platelet aggregation induced by platelet-activating factor (PAF). When added separately, neither histamine nor chloropyramine, a competitive antagonist of H1 receptors, influenced platelet aggregation, however BN 52021, a specific PAF
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