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Merck
CN

C0682000

Cefalotin sodium

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Cephalothin sodium salt, 7-(2-Thienylacetamido)cephalosporanic acid sodium salt, Cephalotin sodium salt

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About This Item

Empirical Formula (Hill Notation):
C16H15N2NaO6S2
CAS Number:
58-71-9
Molecular Weight:
418.42
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329774809
MDL number:
MFCD00072025
Beilstein/REAXYS Number:
4120706

Key Documents

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Product Name

Cefalotin sodium, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1

SMILES string

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O

InChI key

VUFGUVLLDPOSBC-XRZFDKQNSA-M

grade

pharmaceutical primary standard

API family

cefalotin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Cefalotin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.

Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.

Mode of Resistance: Production of cephalosporinase will inactivate the product.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Ming-Han Hugo Lee et al.
Journal of glaucoma, 24(1), 87-88 (2013-08-24)
One recognized complication of trabeculectomy with visually devastating potential is blebitis. We present a case of a 74-year-old woman with a culture and polymerase chain reaction-positive Abiotrophia defectiva bleb-associated endophthalmitis. Abiotrophia defectiva is a rare but possible cause of endophthalmitis

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