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BP882

α-Tocopherol

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

(±)-α-Tocopherol, DL-all-rac-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
10191-41-0
Molecular Weight:
430.71
Beilstein:
94012
EC Number:
233-466-0
MDL number:
MFCD00006848
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

tocopherol

form

solid

manufacturer/tradename

BP

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

color

light yellow

mp

2.5-3.5 °C

density

0.950 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. α -Tocopherol is the active form of vitamin E. It functions as an hydroperoxyl radical scavenger and protects from oxidative damage. α -Tocopherol plays a crucial role in cell signalling and regulating immune responses. α -Tocopherol deficiency is associated with abetalipoproteinemia, cystic fibrosis and celiac disease. It has antiproliferative effects. It inhibits arsenite-induced damage of human fibroblasts.

Application

Α-Tocopherol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Alpha Tocopheryl Succinate Tablets

    • Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    Pictograms

    Exclamation mark
    GHS07

    Signal Word

    Warning

    Hazard Statements

    H317

    Hazard Classifications

    Skin Sens. 1

    WGK

    WGK 1

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    Certificates of Analysis (COA)

    Lot/Batch Number

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    Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatography
    Arnaud J, et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 572(1-2), 103-116 (1991)

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