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Merck
CN

BP867

Losartan potassium

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol monopotassium salt, 2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]- 1H-Imidazole-5-methanol potassium salt, DuP 753, MK 954, Potassium 5-(4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-ide

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About This Item

Empirical Formula (Hill Notation):
C22H22ClKN6O
CAS Number:
124750-99-8
Molecular Weight:
461.00
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
5845770
MDL number:
MFCD02092704

Key Documents

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Product Name

Losartan potassium, British Pharmacopoeia (BP) Reference Standard

SMILES string

CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]

InChI key

OXCMYAYHXIHQOA-UHFFFAOYSA-N

InChI

1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1

grade

pharmaceutical primary standard

API family

losartan

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... AGTR1(185)

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Related Categories

Application

Losartan potassium BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Losartan Potassium Tablets

    • Biochem/physiol Actions

    Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.
    orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Storage Class

    11 - Combustible Solids

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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