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BP793

Budesonide

British Pharmacopoeia (BP) Reference Standard

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Synonym(s):
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
Empirical Formula (Hill Notation):
C25H34O6
CAS Number:
51333-22-3
Molecular Weight:
430.53
MDL number:
MFCD00083259
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

budesonide

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(CCC)O[C@@]45C(=O)CO

InChI

1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

InChI key

VOVIALXJUBGFJZ-KWVAZRHASA-N

Gene Information

human ... NR3C1(2908)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Budesonide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Budesonide Aqueous Nasal Spray
  • Budesonide Inhalation Powder, pre-metered
  • Budesonide Inhalation Powder
  • Budesonide Pressurised Inhalation
  • Budesonide Nebuliser Suspension

    • Biochem/physiol Actions

    Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.

    Packaging

    Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

    Product No.
    Description
    Pricing

    PHR1178

    Budesonide, Pharmaceutical Secondary Standard; Certified Reference Material

    B1157300

    Budesonide, European Pharmacopoeia (EP) Reference Standard

    Y0001148

    Budesonide for system suitability, European Pharmacopoeia (EP) Reference Standard

    1078201

    Budesonide, United States Pharmacopeia (USP) Reference Standard

    1078289

    Budesonide Related Compound L, United States Pharmacopeia (USP) Reference Standard

    1078267

    Budesonide Related Compound G, United States Pharmacopeia (USP) Reference Standard

    1078245

    Budesonide Related Compound E, United States Pharmacopeia (USP) Reference Standard

    PHR1823

    Budesonide Related Compound L, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1822

    Budesonide Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

    BP894

    Budesonide impurity standard, British Pharmacopoeia (BP) Reference Standard

    Pictograms

    Health hazardExclamation mark
    GHS08,GHS07

    Signal Word

    Danger

    Hazard Statements

    H302,H317,H361d,H372,H412

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

    Target Organs

    Adrenal gland

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Regulatory Information

    监管及禁止进口产品

    Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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