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BP578

Dexamethasone

British Pharmacopoeia (BP) Assay Standard

Synonym(s):

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

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About This Item

Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
50-02-2
Molecular Weight:
392.46
Beilstein:
2066651
EC Number:
200-003-9
MDL number:
MFCD00064136
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dexamethasone

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

262-264 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

Gene Information

human ... NR3C1(2908)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Tobramycin and Dexamethasone Eye Drops, Suspension
  • Dexamethasone Sodium Phosphate Oral Solution
  • Hydrocortisone Sodium Succinate Injection
  • Prednisolone Tablets
  • Dexamethasone Eye Drops, Suspension
  • Dexamethasone Sodium Phosphate Eye Drops, Solution
  • Dexamethasone and Neomycin Ear Spray
  • Betamethasone Tablets
  • Dexamethasone Tablets

    • Biochem/physiol Actions

    Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

    Other Notes

    Sales restrictions may apply.

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    Dexamethasone sodium phosphate for peak identification, European Pharmacopoeia (EP) Reference Standard

    Y0001593

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    1176506

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    1176007

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    Pictograms

    Health hazard
    GHS08

    Signal Word

    Danger

    Hazard Statements

    H360FD

    Hazard Classifications

    Repr. 1B

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Regulatory Information

    监管及禁止进口产品

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    Lot/Batch Number

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