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BP197

Hydroxycarbamide

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Hydroxyurea, Hydroxycarbamide

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About This Item

Linear Formula:
NH2CONHOH
CAS Number:
127-07-1
Molecular Weight:
76.05
Beilstein:
1741548
MDL number:
MFCD00007943
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

hydroxycarbamide

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

NC(=O)NO

InChI

1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)

InChI key

VSNHCAURESNICA-UHFFFAOYSA-N

Gene Information

human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydroxycarbamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Hydroxycarbamide Capsules

    • Biochem/physiol Actions

    Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

    Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

    Product No.
    Description
    Pricing

    Pictograms

    Health hazard
    GHS08

    Signal Word

    Danger

    Hazard Statements

    H340,H361

    Hazard Classifications

    Muta. 1B - Repr. 2

    Storage Class Code

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

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    Certificates of Analysis (COA)

    Lot/Batch Number

    Sorry, we don't have COAs for this product available online at this time.

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