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BP1144

Glimepiride

British Pharmacopoeia (BP) Reference Standard

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Empirical Formula (Hill Notation):
C24H34N4O5S
CAS Number:
93479-97-1
Molecular Weight:
490.62
MDL number:
MFCD00878417
UNSPSC Code:
12352200
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

glimepiride

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O

InChI

1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-

InChI key

WIGIZIANZCJQQY-RUCARUNLSA-N

Gene Information

human ... ABCC8(6833) , KCNJ11(3767)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glimepiride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Glimepiride Tablets
    • Glimepiride is currently used to treat type 2 diabetes.

    Biochem/physiol Actions

    Glimepiride is a potent blocker of cardiac KATP channels activated by pinacidil with an IC50 of 6.8 nM.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

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    1292325

    Glimepiride Related Compound B, United States Pharmacopeia (USP) Reference Standard

    Y0000516

    Glimepiride for system suitability, European Pharmacopoeia (EP) Reference Standard

    Y0000515

    Glimepiride, European Pharmacopoeia (EP) Reference Standard

    1292314

    Glimepiride Related Compound A, United States Pharmacopeia (USP) Reference Standard

    1292336

    Glimepiride Related Compound C, United States Pharmacopeia (USP) Reference Standard

    1292347

    Glimepiride Related Compound D, United States Pharmacopeia (USP) Reference Standard

    Y0001742

    Glimepiride for impurity A identification, European Pharmacopoeia (EP) Reference Standard

    PHR1617

    Glimepiride, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1727

    Glimepiride Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1725

    Glimepiride cis-Isomer (Glimepiride Related Compound A), Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1726

    Glimepiride Sulfonamide, pharmaceutical secondary standard, certified reference material

    Pictograms

    Health hazard
    GHS08

    Signal Word

    Warning

    Hazard Statements

    H361

    Hazard Classifications

    Repr. 2

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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