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BP016

Amitriptyline hydrochloride

British Pharmacopoeia (BP) Reference Standard

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Empirical Formula (Hill Notation):
C20H23N · HCl
CAS Number:
549-18-8
Molecular Weight:
313.86
MDL number:
MFCD00012537
UNSPSC Code:
12352200
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amitriptyline

form

powder

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13

InChI

1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

InChI key

KFYRPLNVJVHZGT-UHFFFAOYSA-N

Gene Information

human ... SLC6A2(6530) , SLC6A4(6532)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amitriptyline hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Amitriptyline Oral Solution
  • Amitriptyline Tablets

    • Biochem/physiol Actions

    Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

    Packaging

    Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

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    Pricing

    1029002

    Amitriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard

    D1000000

    Dibenzosuberone, European Pharmacopoeia (EP) Reference Standard

    PHR1384

    Amitriptyline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    Y0000563

    Amitriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard

    1029013

    Amitriptyline Related Compound A, United States Pharmacopeia (USP) Reference Standard

    1029024

    Amitriptyline Related Compound B, United States Pharmacopeia (USP) Reference Standard

    PHR1776

    Amitriptyline Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

    BP858

    Dibenzosuberone, British Pharmacopoeia (BP) Reference Standard

    PHR2836

    Amitriptyline Related Compound A, certified reference material, pharmaceutical secondary standard

    Signal Word

    Danger

    Hazard Statements

    H301,H319,H361d,H410

    Hazard Classifications

    Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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