BCR265
Dibenzo[a,e]fluoranthene
BCR®, certified reference material
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C24H14
Recommended Products
grade
certified reference material
Agency
BCR®
manufacturer/tradename
JRC
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
SMILES string
c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35
InChI
1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H
InChI key
JHOWUOKQHJHGMU-UHFFFAOYSA-N
Analysis Note
For more information please see:
BCR265
BCR265
Legal Information
BCR is a registered trademark of European Commission
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Carcinogenesis, 4(7), 827-835 (1983-01-01)
The metabolism of the polycyclic hydrocarbon dibenzo[a,e]fluoranthene (DBF) has been investigated. Two new primary metabolites have been identified by proton n.m.r. as the trans diaxial dihydrodiols of the bay and of the pseudo bay regions of DBF. In addition, twelve
Chemico-biological interactions, 37(1-2), 109-122 (1981-10-01)
The effects of norharman (NH) on the metabolism of dibenzo[a,e]-fluoranthene (DBF) and on its fixation on DNA, RNA and proteins have been studied in vitro by incubation with S-9 and microsomes from rats and mice. NH causes a decrease of
Carcinogenesis, 9(8), 1383-1388 (1988-08-01)
The three-dimensional distribution of nuclear DNA damage induced by dibenzo(a,e)fluoranthene (DBF), a potent carcinogen for mouse fibroblasts, has been examined. The intact supercoiled nuclear DNA obtained from nucleoids of mouse fibroblasts incubated with DBF was fractionated into loop DNA attached
Carcinogenesis, 11(2), 301-306 (1990-02-01)
The formation of DNA adducts was investigated in mouse fibroblasts treated with dibenzo[a,e]fluoranthene (DBF), using the nuclease P1 modification of the 32P-post-labeling method. In order to separate the poorly soluble, bulky DNA adducts of this potent sarcomogenic, six-ring polycyclic aromatic
Cancer letters, 22(3), 289-298 (1984-04-01)
Dibenzo[a,e]fluoranthene ( DBF ), a non- alternant carcinogenic polycyclic aromatic hydrocarbon (PAH), binds covalently to DNA. The main adducts were characterized as covalent additions of its bay-region and pseudo-bay-region diol-epoxides. The structure of these 2 adducts was analyzed by mass
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