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BCR158

Benz[c]acridine

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C17H11N
CAS Number:
225-51-4
Molecular Weight:
229.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329773794
MDL number:
MFCD00215933
Beilstein/REAXYS Number:
154999

Key Documents

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InChI

1S/C17H11N/c1-3-7-15-12(5-1)9-10-14-11-13-6-2-4-8-16(13)18-17(14)15/h1-11H

SMILES string

c1ccc2nc3c(ccc4ccccc34)cc2c1

InChI key

OAPPEBNXKAKQGS-UHFFFAOYSA-N

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

Related Categories

Analysis Note

For more information please see:
BCR158

Legal Information

BCR is a registered trademark of European Commission

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H302,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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H Sakagami et al.
Anticancer research, 15(6B), 2533-2540 (1995-11-01)
A series of phenothiazine, benzo[a]phenothiazine and benz[c]acridine derivatives were compared for their ability to induce nucleosome-sized DNA fragmentation (a biochemical hallmark of apoptosis), using agarose gel electrophoresis and a fluorescence activated cell sorter. Significant DNA fragmentation-inducing activity was detected in
T Kurihara et al.
Anticancer research, 18(1A), 429-432 (1998-05-06)
On the calculated pi-spin density (rho pi) of benz[c]acridines [1-12], benz[c]acridines [2,8-12] with alternately value of pi-spin density (rho pi) on angular ring, large negative pi-spin density at C-1 and C-3 positions and large positive pi-spin density at C-2 and
K Kamata et al.
Anticancer research, 9(3), 579-582 (1989-05-01)
Raman spectra of methyl substituted benz[c]acridines (BAc) in the solid state were recorded. Their assignments were proposed for the frequencies of Raman spectra observed. The purpose of this work was to elucidate the mechanisms of interaction between BAc and DNA
M Tanaka et al.
Anticancer research, 16(5A), 2837-2841 (1996-09-01)
The mutagenicity of eleven methylbenz[c]acridines (methyl-B[c]ACRs) was examined by the direct Ames' Salmonella mutagenicity assay on the standard tester strains of TA97a, TA98, TA100 and TA102, each of which is specific to a certain type of mutation. The Benz[c]acridines (B[c]ACRs)
T Kurihara et al.
Anticancer research, 16(5A), 2757-2765 (1996-09-01)
In order to clarify the effects of methyl substitution on the carcinogenic activity, each resonance energy (RE) of benz[c]acridines, benzo[a]phenothiazines, chrysene, and their methyl derivatives was calculated by Aihara's TRE theory. Some correlations seem to exist between the values of
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