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A5431

Sigma-Aldrich

Noble agar

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Synonym(s):
Agar, Agar-agar, Gum agar
Linear Formula:
(C12H18O9)n
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
50405901
NACRES:
NA.75

form

powder

Quality Level

application(s)

food and beverages

InChI

1S/C14H24O9/c1-5-8(16)13-11(7(21-5)4-20-13)23-14-10(18)12(19-2)9(17)6(3-15)22-14/h5-18H,3-4H2,1-2H3/t5?,6-,7?,8-,9+,10-,11?,12+,13+,14?/m1/s1

InChI key

GYYDPBCUIJTIBM-DYOGSRDZSA-N

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General description

Noble agar, also known as agar or agar-agar, is a gelling hydrocolloid extracted from sea weeds such as Gelidium and Gracilaria. It′s structure contains repeating units of D-galactose and 3,6-anhydro-L-galactose, with a few differences, in addition to a low ester sulphate residue. Agarose and agaropectin are the key components of agar. Noble agar is majorly used as both human and animal food supplement. In addition, it is also used in industries for the preparation of solid microbiological media.

Application

Noble agar has been used as a component of growth medium for High grade serous ovarian cancer (HGSOC) cell lines for soft agar colony assay. It has also been used as a media component to culture anaerobic bacteria, Bacteroides thetaitaomicron
Noble agar has been used to make agar gel plates that acts as a standard solid support material:
  • to culture tumor spheroids
  • in lysoplate assay method of Osserman & Lawlor to measure lysozyme concentration in albumen or plasma
  • as BG11 media component to culture Scenedesmus obtusiusculus strains
Originally designed for use in Noble′s cyanide citrate agar.

Preparation Note

Further purified from bacteriological agar with careful specific washings.

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Effect of restricted preen-gland access on maternal self maintenance and reproductive investment in mallards
Giraudeau M, et al.
PLoS ONE, 5(10), e13555-e13555 (2010)
Agar and agarose biotechnological applications
Armisen R
Hydrobiologia, 157-166 (1991)
Maternal investment of female mallards is influenced by male carotenoid-based coloration
Giraudeau M, et al.
Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character. Royal Society (Great Britain), 278(1706), 781-788 (2010)
Characterization of Scenedesmus obtusiusculus AT-UAM for high-energy molecules accumulation: deeper insight into biotechnological potential of strains of the same species
Toledo-Cervantes A, et al.
Biotechnology reports (Amsterdam, Netherlands), 17, 16-23 (2018)
Structure of the agarose constituent of agar-agar
Araki C, et al.
Bulletin of the Chemical Society of Japan, 29(4), 543-544 (1956)

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