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A0650000

Amobarbital

European Pharmacopoeia (EP) Reference Standard

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Empirical Formula (Hill Notation):
C11H18N2O3
CAS Number:
57-43-2
Molecular Weight:
226.27
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amobarbital

manufacturer/tradename

EDQM

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key

VIROVYVQCGLCII-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amobarbital EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H336,H361d,H412

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Kurthen
Der Nervenarzt, 63(12), 713-724 (1992-12-01)
In presurgical assessment of epilepsy, the intracarotid amobarbital procedure (IAP) is used for the detection of functional asymmetries of the cerebral hemispheres with respect to cognitive functions. The IAP permits a precise and reliable determination of patterns of language dominance
Role of the neuropsychological evaluation and the intracarotid sodium amobarbital procedure in the surgical treatment for epilepsy.
R Rausch
Epilepsy research. Supplement, 5, 77-86 (1992-01-01)
Evidence-based practice: a reevaluation of the intracarotid amobarbital procedure (Wada test).
Sallie A Baxendale et al.
Archives of neurology, 65(6), 841-845 (2008-06-11)
M Kurthen et al.
Der Radiologe, 33(4), 204-212 (1993-04-01)
In presurgical evaluation of epilepsy, unilateral cerebral inactivation by means of intracarotid injection of amobarbital is used for the determination of cerebral dominance for language and memory functions. This intracarotid amobarbital test (IAT) is intended to yield prognoses concerning postsurgical
Akta Patel et al.
The Annals of pharmacotherapy, 45(3), 395-401 (2011-02-18)
To review the literature and identify alternatives to sodium amobarbital for use in the Wada test. A search of PubMed (1960-October 2010) was performed using the following key words alone or in combination: Wada test, intracarotid amobarbital procedure, intracarotid, intraarterial
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