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Safety Information

A0650000

Amobarbital

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C11H18N2O3
CAS Number:
57-43-2
Molecular Weight:
226.27
MDL number:
MFCD00057558
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amobarbital

manufacturer/tradename

EDQM

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key

VIROVYVQCGLCII-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amobarbital EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H336,H361d,H412

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

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Commentary: Epilepsia's Wada survey.
David Loring
Epilepsia, 55(12), 1891-1891 (2014-11-02)
J N Acharya et al.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 14(4), 311-325 (1997-07-01)
The intracarotid amobarbital procedure (IAP) involves the temporary inactivation of one cerebral hemisphere by the injection of sodium amobarbital, which allows independent testing of the contralateral hemisphere. Initially used for lateralization of language, IAP later found a role in the
Commentary: Epilepsia's Wada survey.
Andrew C Papanicolaou
Epilepsia, 55(12), 1890-1890 (2014-11-02)
M Kurthen
Fortschritte der Neurologie-Psychiatrie, 61(3), 77-89 (1993-03-01)
In neuropsychological diagnostics of lateralisation of cognitive functions, the intracarotid amobarbital procedure (IAP) is a well established method for the determination of cerebral language dominance. In this review, different frameworks of classification of dominance patterns are discussed, ranging from the
Ashwini Sharan et al.
Epilepsy & behavior : E&B, 20(2), 209-213 (2010-12-31)
The intracarotid amobarbital procedure (IAP) has been used for more than half a century to determine language dominance and to assess risk for amnesia after anterior temporal lobectomy. However, because of the risk associated with angiography and the development of
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