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Merck
CN

95082

Chrysin

analytical standard

Synonym(s):

5,7-Dihydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
Molecular Weight:
254.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-549-7
Beilstein/REAXYS Number:
233276
MDL number:
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Product Name

Chrysin, analytical standard

InChI

1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccccc3

InChI key

RTIXKCRFFJGDFG-UHFFFAOYSA-N

grade

analytical standard

assay

≥98% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

284-286 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chrysin is a naturally occurring mono-flavonoid , which is present in plant cells involved in photosynthesis. It may possess a broad spectrum of pharmacological properties like antioxidant, anti-viral, anti-inflammatory, anxiolytic and vasodilatory effects.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Principles of Orthomolecularism (2004)
Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea
Wolfman C, et al.
Pharmacology, Biochemistry, and Behavior, 47(1), 1-4 (1994)
Alexandrine During et al.
Biochemical pharmacology, 86(12), 1739-1746 (2013-10-19)
The aim of this study was to investigate whether methoxylated flavones versus their unmethylated analogs can modulate the intestinal inflammatory response. Flavone effects were assessed on soluble pro-inflammatory mediator (IL-8, IL-6, macrophage chemoattractant protein-1 (MCP-1), and cyclooxygenase-2 (COX-2)-derived PGE2) production
Xiao-Li He et al.
European journal of pharmacology, 680(1-3), 41-48 (2012-02-09)
Chronic cerebral hypoperfusion, induced by permanent occlusion of bilateral common carotid arteries (2VO), is related to neurological disorders and contributes to cognitive decline. Chrysin (5,7-dihydroxyflavone) is an important member of the flavonoid family. The aim of this study is to
Chin-Shiu Huang et al.
Archives of toxicology, 87(1), 167-178 (2012-08-07)
Chrysin, apigenin, and luteolin are flavones that differ in their number of hydroxyl groups in the B ring. In this study, we investigated the protection by chrysin, apigenin, and luteolin against tert-butyl hydroperoxide (tBHP)-induced oxidative stress and the possible mechanisms

Protocols

HPTLC fingerprinting enables rapid identification of passion flower with related reference materials.

Qualitative Thin Layer Chromatography Analysis of Flavonoids and Quantification of Terpene Lactones in Ginkgo Biloba Extracts and Tablets

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