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94972

Supelco

Brombuterol hydrochloride

VETRANAL®, analytical standard

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Synonym(s):
1-(4-Amino-3,5-dibromophenyl)-2-tert-butylaminoethanol hydrochloride
Empirical Formula (Hill Notation):
C12H18Br2N2O · HCl
CAS Number:
21912-49-2
Molecular Weight:
402.55
MDL number:
MFCD10567368
UNSPSC Code:
41116107
PubChem Substance ID:
329770406
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

Assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.CC(C)(C)NCC(O)c1cc(Br)c(N)c(Br)c1

InChI

1S/C12H18Br2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

InChI key

XGPFKIAOVSGRSY-UHFFFAOYSA-N

Related Categories

General description

Brombuterol hydrochloride is a beta-sympathomimetic compound with tocolytic, muscle-relaxant and bronchodilator properties and is widely used in therapy for their growth promoting and performance enhancement.

Application

Brombuterol hydrochloride may be used as an analytical reference standard for the quantification of the analyte in complex matrices and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C Montesissa et al.
Xenobiotica; the fate of foreign compounds in biological systems, 28(11), 1049-1060 (1999-01-08)
1. Clenbuterol (CBL) and bromobuterol (BBL) were both extensively metabolized by hepatic microsomes of swine to only one polar metabolite which was separated by hplc and purified to perform mass analysis. 2. LC-MIS analysis by direct infusion into an ion
E Sangiorgi et al.
Journal of chromatography. B, Biomedical sciences and applications, 693(2), 468-478 (1997-06-06)
The multistep analytical procedure routinely applied in our laboratory for the detection of the aryl amine beta-agonists clenbuterol, mabuterol and mapenterol in bovine matrices has been extended to the analysis in urine samples of brombuterol, a new clenbuterol-like compound. In
Leslie C Dickson et al.
Journal of AOAC International, 88(1), 46-56 (2005-03-12)
A multiresidue method was developed and validated to screen bovine urine samples for 10 beta-2-adrenergic agonistic drugs--brombuterol, cimaterol, clenbuterol, clenpenterol, isoxsuprine, mabuterol, ractopamine, ritodrine, salbutamol, and tulobuterol--at the 2 microg/L level. The method is also quantitative in the range of
Analysis of beta-agonist residues in bovine hair: Development of a UPLC?MS/MS method and stability study
Giannetti L, et al.
Journal of Chromatography. B, Biomedical Applications, 1036(3), 76-83 (2016)
Overcoming matrix effects in electrospray: Quantitation of ?-agonists in complex matrices by isotope dilution liquid chromatography?mass spectrometry using singly 13C-labeled analogues
Gonzalez-Antuna A, et al.
Journal of Chromatography A, 40-47 (2013)
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