93440
Trizma® base
≥99.5%, solid, certified reference material, certified by BAM
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Synonym(s):
2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
reference material
Quality Level
description
aminopeptidase substrate
Assay
≥99.5%
quality
certified by BAM
technique(s)
titration: suitable
pH
10.5-12
useful pH range
7-9
pKa (25 °C)
8.1
bp
219-220 °C/10 mmHg (lit.)
mp
167-172 °C (lit.)
solubility
water: soluble (678 g/l at 20 °C)
format
neat
SMILES string
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
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General description
Trizma® base is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content is determined by volumetric neutralization titration using a combined pH glass electrode. The certified value and uncertainty measurement of the standard are in accordance with ISO Guide 35.
Application
It finds its use as a reference material for the standardization of volumetric solutions in acidimetric titrations.
Features and Benefits
- Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened.
- High-purity material traceable to NIST SRM
- High-quality offering accurate titer determinations
- Accompanied by a certificate of analysis (CoA)
Analysis Note
Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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