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Safety Information

93303

Sigma-Aldrich

Tris(2-aminoethyl)amine

technical, ≥90% (GC)

Synonym(s):

2,2′,2′′-Nitrilotriethylamine, 2,2′,2′′-Triaminotriethylamine, TAEA

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About This Item

Linear Formula:
(NH2CH2CH2)3N
CAS Number:
4097-89-6
Molecular Weight:
146.23
Beilstein:
1739626
EC Number:
223-857-4
MDL number:
MFCD00008177
UNSPSC Code:
12162002
PubChem Substance ID:
329770222

vapor density

5 (vs air)

vapor pressure

0.02 mmHg ( 20 °C)

grade

technical

Assay

≥90% (GC)

refractive index

n20/D 1.497 (lit.)
n20/D 1.497

bp

114 °C/15 mmHg (lit.)

density

0.976 g/mL at 20 °C (lit.)

SMILES string

NCCN(CCN)CCN

InChI

1S/C6H18N4/c7-1-4-10(5-2-8)6-3-9/h1-9H2

InChI key

MBYLVOKEDDQJDY-UHFFFAOYSA-N

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Paloma Arranz et al.
Inorganic chemistry, 49(20), 9321-9332 (2010-09-15)
Binding of anions of great environmental concern such as SO(4)(2-), PO(4)(3-), AsO(4)(3-), HgCl(4)(2-), and CrO(4)(2-) by the protonated forms of a tren-like (tren = tris(2-aminoethyl)amine) ligand (HL) functionalized with a pyrimidine residue was studied by means of potentiometric measurements and
Sulfate recognition by persistent crystalline capsules with rigidified hydrogen-bonding cavities.
Radu Custelcean et al.
Angewandte Chemie (International ed. in English), 47(10), 1866-1870 (2008-02-01)
Pascal Dimitrov Raytchev et al.
The Journal of organic chemistry, 75(6), 2099-2102 (2010-02-20)
The first hemicryptophanes derived from tris(N-alkyl-carbamoylmethyl)amine and tris(2-aminoethyl)amine (tren) have been synthesized following a single synthetic pathway that allows the subsequent formation of the two heteroditopic hosts 3 and 4. X-ray crystal structures show a well-defined cavity encapsulating a solvent
Cynthia T Brewer et al.
Dalton transactions (Cambridge, England : 2003), 40(1), 181-194 (2010-11-26)
Reaction of H(3)L(1), the Schiff base condensate of tris(2-aminoethyl)amine with three equivalents of 5-methyl-1H-pyrazole-3-carboxaldehyde, with manganese(II)perchlorate or iron(II)tetrafluoroborate results in the isolation of [MH(3)L(1)]X(2) (M = Mn and X = ClO(4) and M = Fe and X = BF(4)). These
Bo Yu et al.
Biomaterials, 33(25), 5924-5934 (2012-06-02)
Clinical application of small interfering RNA (siRNA) requires safe and efficient delivery in vivo. Here, we report the design and synthesis of lipid nanoparticles (LNPs) for siRNA delivery based on cationic lipids with multiple tertiary amines and hydrophobic linoleyl chains. LNPs
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