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Merck
CN

92321

Conjugated (10E,12Z)-Linoleic acid

analytical standard

Synonym(s):

(10E,12Z)-10,12-Octadecadienoic acid, 10E,Z12-CLA, Linoleic acid (10-trans, 12-cis)

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About This Item

Empirical Formula (Hill Notation):
C18H32O2
CAS Number:
2420-56-6
Molecular Weight:
280.45
UNSPSC Code:
85151701
PubChem Substance ID:
329769886
MDL number:
MFCD02259040

Key Documents

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InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-9H,2-5,10-17H2,1H3,(H,19,20)/b7-6-,9-8+

SMILES string

CCCCC/C=C\C=C/CCCCCCCCC(O)=O

InChI key

GKJZMAHZJGSBKD-NMMTYZSQSA-N

biological source

synthetic

grade

analytical standard

assay

≥96.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

functional group

carboxylic acid

storage temp.

−20°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR5309V

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Han Su et al.
Food & function, 11(4), 3657-3667 (2020-04-17)
This study aimed to investigate the effects of conjugated linoleic acid (CLA) on intestinal epithelial barrier function and explore the underlying mechanisms. IPEC-J2 cells and mice were treated with different CLA isomers. The intestinal epithelial barrier function determined by transepithelial
Satoru Tamura et al.
Bioorganic & medicinal chemistry letters, 20(6), 1837-1839 (2010-02-24)
Bioassay-guided separation from the MeOH extract of the South American medicinal plant Sida cordifolia resulted in isolation of (10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid (1) as an unprecedented NES non-antagonistic inhibitor for nuclear export of Rev. This mechanism of action was established by competitive

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