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Merck
CN

92168

Homogentisic acid

analytical standard

Synonym(s):

2,5-Dihydroxyphenylacetic acid

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About This Item

Linear Formula:
(HO)2C6H3CH2CO2H
CAS Number:
Molecular Weight:
168.15
EC Number:
207-192-7
UNSPSC Code:
12352106
NACRES:
NA.24
Beilstein/REAXYS Number:
2692860
MDL number:
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Product Name

Homogentisic acid, analytical standard

InChI key

IGMNYECMUMZDDF-UHFFFAOYSA-N

InChI

1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

SMILES string

OC(=O)Cc1cc(O)ccc1O

grade

analytical standard

assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

mp

150-152 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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Application

Homogentisic acid may be used as an analytical reference standard for the determination of the analyte in strawberry tree honey samples, urine samples and biological fluids using chromatography based techniques.

General description

Homogentisic acid is a phenolic acid which is obtained as an intermediate, in the catabolism of tyrosine and phenylalanine.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Homogentisic acid: a phenolic acid as a marker of strawberry-tree (Arbutus unedo) honey
Cabras P, et al.
Journal of Agricultural and Food Chemistry, 47(10), 4064-4067 (1999)
Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines (2019)
Determination of homogentisic acid in serum and urine by liquid chromatography with amperometric detection
Zoutendam HP, et al.
Analytical Chemistry, 48(14), 2200-2202 (1976)
Direct chromatographic methods for the rapid determination of homogentisic acid in strawberry tree (Arbutus unedo L.) honey
Scanu R, et al.
Journal of Chromatography A, 1090(1-2), 76-80 (2005)
Urine homogentisic acid and tyrosine: simultaneous analysis by liquid chromatography tandem mass spectrometry
Hughes TA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 963, 106-112 (2014)

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