917362
2-(4-(1-(tert-butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid
≥95%
Synonym(s):
Semi-flexible linker for PROTAC® development
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C18H25NO4
CAS Number:
Molecular Weight:
319.40
UNSPSC Code:
12352106
NACRES:
NA.22
Quality Level
Assay
≥95%
form
powder
reaction suitability
reagent type: linker
mp
164-170 °C
functional group
Boc
carboxylic acid
storage temp.
2-8°C
SMILES string
O=C(OC(C)(C)C)N1CCC(C2=CC=C(CC(O)=O)C=C2)CC1
Related Categories
Application
2-(4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
related product
Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service