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Safety Information

909750

Sigma-Aldrich

6-Azido-L-lysine hydrochloride

≥95%

Synonym(s):

(S)-2-Amino-6-azidohexanoic acid hydrochloride, 6-Azido-L-lysine HCl, N-ε-Azido-L-lysine, H-L-Lys(N3)-OH*HCl

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About This Item

Empirical Formula (Hill Notation):
C6H12N4O2 · HCl
Molecular Weight:
208.65
UNSPSC Code:
12352209

Assay

≥95%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

availability

available only in USA

storage temp.

2-8°C

Application

The in vivo incorporation of clickable unnatural amino acids such as 6-Azido-L-lysine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H242

Hazard Classifications

Self-react. C

Storage Class Code

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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