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Safety Information

90605

Sigma-Aldrich

1,5,7-Triazabicyclo[4.4.0]dec-5-ene

purum, ≥98.0% (T)

Synonym(s):

1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, Hhpp, TBD

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About This Item

Empirical Formula (Hill Notation):
C7H13N3
CAS Number:
Molecular Weight:
139.20
Beilstein:
3242
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

grade

purum

Assay

≥98.0% (T)

mp

125-130 °C (lit.)
125-132 °C

solubility

toluene: 1 g/15 mL

SMILES string

C1CNC2=NCCCN2C1

InChI

1S/C7H13N3/c1-3-8-7-9-4-2-6-10(7)5-1/h1-6H2,(H,8,9)

InChI key

FVKFHMNJTHKMRX-UHFFFAOYSA-N

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Other Notes

Guanidine base which is about 100 times more basic than tetramethylguanidine; Powerful base for tautomerizing pyrrocorphins and for other reactions

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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K. Hilpert et al.
Journal of the Chemical Society. Chemical Communications, 1401-1401 (1983)
U. Kampfen et al.
Helvetica Chimica Acta, 72, 185-185 (1989)
Jinfeng Wang et al.
PloS one, 10(2), e0118086-e0118086 (2015-02-24)
MicroRNA-214 (miR-214) has been reported to be dysregulated in human bladder cancer tissues. We aimed to investigate the clinical correlation, biological significance and molecular network of miR-214 in bladder cancer. Our results showed miR-214 was down-regulated in bladder cancer tissues
R. Schwesinger
Chimia, 39, 269-269 (1985)
Shouru Zhang et al.
Medical oncology (Northwood, London, England), 32(1), 414-414 (2014-12-05)
The mammalian peroxiredoxin 2 (Prdx2) is a member of thiol-dependent antioxidant proteins and plays an important role in the progression of colorectal cancer (CRC). The aim of this study was to confirm the role of Prdx2 in formation of VM

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