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901767

Sigma-Aldrich

PC biotin-PEG3-NHS ester

Synonym(s):

PC biotin-NHS ester

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5 EA
CN¥768.14

CN¥768.14

Estimated to ship onMay 23, 2025Details

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5 EA
CN¥768.14

About This Item

Empirical Formula (Hill Notation):
C36H52N6O15S
CAS Number:
2353409-93-3
Molecular Weight:
840.89
MDL number:
MFCD31811520
UNSPSC Code:
51171641
NACRES:
NA.22

CN¥768.14

Estimated to ship onMay 23, 2025Details

Request a Bulk Order

form

solid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

mp

170 °C

storage temp.

−20°C

SMILES string

S1[C@H]([C@H]4NC(=O)N[C@H]4C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)ON3C(=O)CCC3=O)C)OC

InChI

1S/C36H52N6O15S/c1-23(56-36(48)57-41-32(45)9-10-33(41)46)24-20-27(51-2)28(21-26(24)42(49)50)55-13-5-8-31(44)38-12-15-53-17-19-54-18-16-52-14-11-37-30(43)7-4-3-6-29-34-25(22-58-29)39-35(47)40-34/h20-21,23,25,29,34H,3-19,22H2,1-2H3,(H,37,43)(H,38,44)(H2,39,

InChI key

WXAMRLAFOFNACR-VTJXTUSFSA-N

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specific activity

~50 U/mg

specific activity

≥1,500 units/mg protein (biuret)

specific activity

300-1,500 units/mg protein

specific activity

1,000-3,000 units/mg protein

form

powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

color

yellow-brown

color

-

color

-

color

-

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

Application

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCW6727
    MKCV8589
    MKCS5656
    MKCQ1420
    MKCL9445

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