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Merck
CN

90139

Schisandrin A

analytical standard

Synonym(s):

Deoxyschisandrin, Deoxyschizandrin, Schizandrin A

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About This Item

Empirical Formula (Hill Notation):
C24H32O6
CAS Number:
61281-38-7
Molecular Weight:
416.51
NACRES:
NA.24
PubChem Substance ID:
329769854
UNSPSC Code:
85151701
MDL number:
MFCD09026934

Key Documents

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InChI

1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+

SMILES string

C[C@@H](C1)[C@H](C)CC2=C(C3=C1C=C(OC)C(OC)=C3OC)C(OC)=C(OC)C(OC)=C2

InChI key

JEJFTTRHGBKKEI-OKILXGFUSA-N

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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General description

Schisandrin A is a lignan, a phytonutrient found mostly in the medicinal plants belonging to the Schisandra species. Lignans are bioactive compounds that can play an important role in preventing liver injuries, carcinogenesis of the liver and lipid peroxidation.

Application

Schisandrin A (Deoxyschisandrin) may be used as an analytical standard for the determination of the analyte in rat plasma and fruits of Schisandra chinensis by chromatography based techniques.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK5417
BCCK7008
BCCJ5003
BCCD4360
BCBV6348

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Simultaneous determination of nine lignans using pressurized liquid extraction and HPLC-DAD in the fruits of Schisandra chinensis
Lee HJ and Kim CY
Food Chemistry, 120(4), 1224-1228 (2010)
Separation and determination of lignans from seeds of Schisandra species by micellar electrokinetic capillary chromatography using ionic liquid as modifier
Tian K, et al.
Journal of Chromatography A, 1078(1-2), 181-187 (2005)
Determination of lignans and phenolic components of Schisandra chinensis (Turcz.) Baill. using HPLC-ESI-ToF-MS and HPLC-online TEAC: Contribution of individual components to overall antioxidant activity and comparison with traditional antioxidant assays
Mocan A, et al.
Journal of functional foods, 24, 579-594 (2016)
Hui Sun et al.
Journal of separation science, 36(3), 485-491 (2013-01-11)
Shengmaisan (SMS) is a traditional Chinese medicine prescription widely used for the treatment of cardiovascular diseases in Asia. Its lignans are major components responsible for therapeutic action. A rapid and specific UPLC-Q-TOF/MS has been developed and validated for simultaneous quantification

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