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Key Documents

89803

Supelco

Methoxyamine hydrochloride

derivatization grade (GC derivatization), LiChropur, 97.5-102.5% (AT)

Synonym(s):

O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride

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50 μG
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50 μG
¥4,485.99

About This Item

Linear Formula:
CH3ONH2 · HCl
CAS Number:
Molecular Weight:
83.52
Beilstein:
3589723
MDL number:
UNSPSC Code:
41116105
NACRES:
NA.05

¥4,485.99


Please contact Customer Service for Availability

Request a Bulk Order

grade

derivatization grade (GC derivatization)

Quality Level

Assay

97.5-102.5% (AT)

form

crystals

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

technique(s)

gas chromatography (GC): suitable

mp

151-154 °C (lit.)

SMILES string

Cl.CON

InChI

1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

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1 of 4

This Item
GE17009002GE17009010G2580
particle size

163 μm (in methanol max.), 27 μm (In Methanol Min.), 18-111 μm (dry)

particle size

163 μm (in methanol max.), 18-111 μm (dry), 27 μm (In Methanol Min.)

particle size

163 μm (in methanol max.), 18-111 μm (dry), 27 μm (In Methanol Min.)

particle size

-

manufacturer/tradename

Cytiva 17-0090-01

manufacturer/tradename

Cytiva 17-0090-02

manufacturer/tradename

Cytiva 17-0090-10

manufacturer/tradename

-

packaging

pack of 100 g

packaging

pack of 500 g

packaging

pack of 25 g

packaging

-

feature

autoclavable 20 min at 121°C

feature

autoclavable 20 min at 121°C

feature

autoclavable 20 min at 121°C

feature

-

cleaning in place

2-13

cleaning in place

2-13

cleaning in place

2-13

cleaning in place

-

General description

Methoxyamine hydrochloride is a commonly used reagent for the generation of oxime derivatives of aldehyde- or ketone-group containing compounds. It is typically employed as an oximation reagent prior to silylation derivatizations.[1][2]

Application

Methoxyamine hydrochloride can be used as:
  • A reagent for the preparation of O-methyl oximes.
  • A reagent used to make O-methyl oximes from aldehydes or ketones.
  • An alkylation reagent.
  • It may be used as a derivatization agent to improve the sensitivity of opioids,[3][4] steroids[5] and ionic metabolites[6] in biological samples and non-volatile flavor compounds in "Angeleno" plum fruit[7] prior to the determination of analytes using gas chromatography-mass spectrometry (GC-MS) technique.

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Solid-phase analytical derivatization for gas-chromatography-mass-spectrometry-based metabolomics
    Takeo E, et al.
    Journal of Bioscience and Bioengineering, 124(6), 700-706 (2017)
    Microwave-assisted derivatization: application to steroid profiling by gas chromatography/mass spectrometry
    Casals G, et al.
    Journal of Chromatography. B, Biomedical Applications, 960(8), 8-13 (2014)
    Optimization of Precolumn Derivatization for Simultaneous Gas Chromatography-Mass Spectrometric Analysis of Non-volatile Flavor Compounds in" Angeleno" Plum Fruit [J]
    HU L, et al.
    Food Science, 14(8), 8-13 (2010)
    Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry.
    Gullberg J, et al.
    Analytical Biochemistry, 331(2), 283-295 (2004)
    GC-MS analysis of multiply derivatized opioids in urine
    Chen BG, et al.
    Journal of Mass Spectrometry : Jms, 42(8), 1012-1023 (2007)

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