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89650

p-Toluidine hydrochloride

Name: <I>p</I>-Toluidine hydrochloride
Brand: SIAL

purum, ≥99.0% (AT)

Synonym(s):

4-Methylaniline hydrochloride

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About This Item

Linear Formula:

CH₃C₆H₄NH₂· HCl

CAS Number:

540-23-8

Molecular Weight:

143.61

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

329769758

EC Number:

208-740-8

Beilstein/REAXYS Number:

3557540

MDL number:

MFCD00035497

Assay:

≥99.0% (AT)

Form:

crystals

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Properties

grade

purum

Quality Level

100

assay

≥99.0% (AT)

form

crystals

mp

243-245 °C (lit.)

SMILES string

Cl[H].Cc1ccc(N)cc1

InChI

1S/C7H9N.ClH/c1-6-2-4-7(8)5-3-6;/h2-5H,8H2,1H3;1H

InChI key

JQKBUTDZZRGQDR-UHFFFAOYSA-N

Description

pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H301 + H311 + H331,H317,H319,H351,H410

pcodes

P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Distinct differences in the mechanisms of mucosal damage and γ-H2AX formation in the rat urinary bladder treated with o-toluidine and o-anisidine.

Takeshi Toyoda et al.

Archives of toxicology, 93(3), 753-762 (2019-01-19)

Although aromatic amines are widely used as raw materials for dyes, some of them have been concerned about carcinogenicity in the urinary bladder. We examined early changes in histopathology and the formation of γ-H2AX, a biomarker of DNA damage, in

Comparison of continuous-flow microextraction and static liquid-phase microextraction for the determination of p-toluidine in Chlamydomonas reinhardtii.

Xiujuan Liu et al.

Journal of separation science, 30(15), 2506-2512 (2007-09-01)

In this study, two microextraction methods, viz. continuous-flow microextraction (CFME) and static liquid-phase microextraction (s-LPME), were optimized and compared for the determination of p-toluidine in water and Chlamydomonas reinhardtii samples. The calibration curve for p-toluidine was linear in the concentration

Spectrophotometric determination of anilines based on charge-transfer reaction.

Hao Wu et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67(3-4), 976-979 (2007-02-03)

The molecular interactions between aniline, p-toluidines, benzidine and p-phenylenediamine as electron donors and 7,7,8,8-tetracyanoquinodimethane (TCNQ) as acceptor have been investigated by spectrophotometric method. Different variables affecting the reaction were studies and optimized. At the optimum reaction conditions Beer's law was

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Global Trade Item Number

SKU	GTIN
89650-100G	04061833076392
89650-500G	04061833076408