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Merck
CN

86608

Tetraethylammonium bromide

suitable for ion pair chromatography, LiChropur™, ≥99.0%

Synonym(s):

TEA bromide

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About This Item

Linear Formula:
(C2H5)4N(Br)
CAS Number:
71-91-0
Molecular Weight:
210.16
UNSPSC Code:
41121813
NACRES:
NB.21
PubChem Substance ID:
329769472
EC Number:
200-769-4
Beilstein/REAXYS Number:
3563430
MDL number:
MFCD00011825
Assay:
≥99.0% (AT), ≥99.0%
Technique(s):
ion pair chromatography: suitable

Key Documents

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Quality Level

100

InChI key

HWCKGOZZJDHMNC-UHFFFAOYSA-M

InChI

1S/C8H20N.BrH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1

SMILES string

[Br-].CC[N+](CC)(CC)CC

description

cationic

assay

≥99.0% (AT), ≥99.0%

form

crystals

quality

LiChropur™

technique(s)

ion pair chromatography: suitable

mp

285 °C (dec.) (lit.)

λ

10 % in H2O

UV absorption

λ: 240 nm Amax: 0.04, λ: 250 nm Amax: 0.03, λ: 260 nm Amax: 0.02, λ: 500 nm Amax: 0.02

suitability

corresponds to standard for filter test

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General description

The use of ion-pairing reagents as mobile phase additives allows the separation of ionic and highly polar substances on reversed phase HPLC columns. The purity of mobile phase additives is of utmost importance to their successful application. Sigma-Aldrich offers an outstanding range of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) determination. All mobile phase additives are subject to rigorous testing with special emphasis on the requirements of modern reversed phase HPLC:

Other Notes

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR6501V

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Karen Mruk et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(34), 13579-13583 (2012-08-08)
Calmodulin (CaM) is a ubiquitous intracellular calcium sensor that directly binds to and modulates a wide variety of ion channels. Despite the large repository of high-resolution structures of CaM bound to peptide fragments derived from ion channels, there is no
Mark A Masino et al.
PloS one, 7(10), e47940-e47940 (2012-10-25)
Conditional neuronal membrane potential oscillations have been identified as a potential mechanism to help support or generate rhythmogenesis in neural circuits. A genetically identified population of ventromedial interneurons, called Hb9, in the mouse spinal cord has been shown to generate
Sébastien Dilly et al.
Biochemical pharmacology, 85(4), 560-569 (2012-12-29)
Valine residues in the pore region of SK2 (V366) and SK3 (V520) were replaced by either an alanine or a phenylalanine to evaluate the impact on the interactions with the allosteric blocker apamin. Unlike TEA which showed high sensitivity to
Gonzalo Budelli et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(41), 16657-16662 (2013-09-27)
High-conductance Ca(2+)- and voltage-activated K(+) (Slo1 or BK) channels (KCNMA1) play key roles in many physiological processes. The structure of the Slo1 channel has two functional domains, a core consisting of four voltage sensors controlling an ion-conducting pore, and a
Guillermo J Pérez et al.
American journal of physiology. Cell physiology, 304(3), C280-C286 (2012-12-01)
We studied principal neurons from canine intracardiac (IC) ganglia to determine whether large-conductance calcium-activated potassium (BK) channels play a role in their excitability. We performed whole cell recordings in voltage- and current-clamp modes to measure ion currents and changes in
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