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Safety Information

86026

Supelco

Sulfadimethoxine

≥99.0% (TLC)

Synonym(s):

4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C12H14N4O4S
CAS Number:
122-11-2
Molecular Weight:
310.33
Beilstein:
306856
EC Number:
204-523-7
MDL number:
MFCD00057345
UNSPSC Code:
12000000
PubChem Substance ID:
24888502

Assay

≥99.0% (TLC)

solubility

1 M NH4OH: 50 mg/mL, clear, faintly yellow

Mode of action

DNA synthesis | interferes
enzyme | inhibits

storage temp.

2-8°C

SMILES string

COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI key

ZZORFUFYDOWNEF-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide

replaced by

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Kyung-Mi Song et al.
Biosensors & bioelectronics, 33(1), 113-119 (2012-01-17)
A polymer-based aptasensor, which consisted of fluorescein amidite (FAM)-modified aptamers and coordination polymer nanobelts (CPNBs), was developed utilizing the fluorescence quenching effect to detect sulfadimethoxine residue in food products. A single-stranded DNA (ssDNA) aptamer, which was a specific bio-probe for
Masamichi Nakayama et al.
Colloids and surfaces. B, Biointerfaces, 99, 12-19 (2011-10-07)
Diblock copolymer comprising thermoresponsive poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) (PIPAAm-co-DMAAm) and hydrophobic poly(benzyl methacrylate) blocks was prepared by reversible addition-fragmentation chain transfer radical polymerization. Terminal functionalization of thermoresponsive blocks with either pH-responsive sulfadimethoxine (SD) or hydroxyl groups was performed through coupling reactions with thiol
Silvia Gazzin et al.
Pediatric research, 71(6), 653-660 (2012-02-18)
Few data exist on regional brain bilirubin content in the neonatal period when acute bilirubin-induced neurologic damage (BIND) may occur, and no information is available on regional brain expression of cytochrome P450 monooxygenases (Cyps) that oxidize bilirubin. Bilirubin content was
Dan Liu et al.
Chemical & pharmaceutical bulletin, 59(1), 63-71 (2011-01-08)
Recently, dendrimers have been widely used in medical applications such as drug delivery and gene transfection. In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. The pK(a) value
Hiroichi Ozaki et al.
Veterinary microbiology, 150(1-2), 132-139 (2011-01-15)
To investigate the effects of rearing practices of commercial broiler chickens on the incidence of antimicrobial resistance in commensal Escherichia coli isolates, fecal E. coli isolates obtained in 4 farms were screened for anitimicrobial resistance. Ten E. coli isolates were
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