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About This Item
Empirical Formula (Hill Notation):
C12H14N4O4S
CAS Number:
Molecular Weight:
310.33
EC Number:
204-523-7
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
306856
MDL number:
InChI key
ZZORFUFYDOWNEF-UHFFFAOYSA-N
InChI
1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
SMILES string
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
assay
≥99.0% (TLC)
solubility
1 M NH4OH: 50 mg/mL, clear, faintly yellow
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
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General description
Chemical structure: sulfonamide
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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Ailiang Chen et al.
Biosensors & bioelectronics, 42, 419-425 (2012-12-12)
Quickly and sensitively detection of antibiotic residues in animal products often requires time-consuming techniques and expensive instrumentation. To address these limitations, a high sensitive aptasensor for sulfadimethoxine (SDM) using unmodified gold nanoparticles (AuNPs) was developed in the present study. The
Dan Liu et al.
Chemical & pharmaceutical bulletin, 59(1), 63-71 (2011-01-08)
Recently, dendrimers have been widely used in medical applications such as drug delivery and gene transfection. In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. The pK(a) value
Lou Ann Tom et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 61-64 (2012-11-17)
Four non-covalently prepared molecularly imprinted polymers (MIPs) for sulfadimethoxine (SDM) were prepared using different ratios of SDM template, methacrylic acid monomer, and ethylene glycol dimethacrylate cross-linker. The imprinting factor (IF) was calculated by comparing the retention of SDM on the
Hiroichi Ozaki et al.
Veterinary microbiology, 150(1-2), 132-139 (2011-01-15)
To investigate the effects of rearing practices of commercial broiler chickens on the incidence of antimicrobial resistance in commensal Escherichia coli isolates, fecal E. coli isolates obtained in 4 farms were screened for anitimicrobial resistance. Ten E. coli isolates were
Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups.
Silvia Gazzin et al.
Pediatric research, 71(6), 653-660 (2012-02-18)
Few data exist on regional brain bilirubin content in the neonatal period when acute bilirubin-induced neurologic damage (BIND) may occur, and no information is available on regional brain expression of cytochrome P450 monooxygenases (Cyps) that oxidize bilirubin. Bilirubin content was
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