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85549

Sigma-Aldrich

Span® 85

Synonym(s):

Sorbitan trioleate, Span® 85

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About This Item

Empirical Formula (Hill Notation):
C60H108O8
CAS Number:
26266-58-0
Molecular Weight:
957.49
EC Number:
247-569-3
MDL number:
MFCD00133820
UNSPSC Code:
12161900
PubChem Substance ID:
24888385

description

non-ionic

refractive index

n20/D 1.476 (lit.)

viscosity

200-300 mPa.s(20 °C)

HLB value

1.8±1.1

density

0.94 g/mL at 20 °C
0.956 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H](CO)[C@H]1OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-52-54(61)59-60(68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)55(53-66-59)67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27+/t54-,55+,59-,60-/m1/s1

InChI key

ZBNRGEMZNWHCGA-WECPCUOASA-N

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Legal Information

Span is a registered trademark of Croda International PLC

replaced by

Product No.
Description
Pricing

S7135

Span® 85

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

437.0 °F

Flash Point(C)

225 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Ming-Hsi Huang et al.
PloS one, 5(8), e12279-e12279 (2010-09-03)
Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5N1 whole-virion vaccine
Gülay Büyükköroğlu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 174-183 (2016-10-30)
Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic agent and a genetic material that
Chen-Yi Chiang et al.
PLoS neglected tropical diseases, 6(5), e1645-e1645 (2012-05-23)
The major weaknesses of subunit vaccines are their low immunogenicity and poor efficacy. Adjuvants can help to overcome some of these inherent defects with subunit vaccines. Here, we evaluated the efficacy of the newly developed water-in-oil-in-water multiphase emulsion system, termed
Theo Jansen et al.
Vaccine, 24(26), 5400-5405 (2006-05-06)
Oil-based emulsions are well-known immunopotentiators for inactivated, "killed" vaccines. We addressed the relationship between emulsion structure and levels of in vivo antibody formation to inactivated New Castle Disease virus (NDV) and Infectious Bronchitis virus (IBV) as antigens in 3-week-old chickens.
Joon Seok Lim et al.
Surgical endoscopy, 26(8), 2267-2274 (2012-02-22)
Pretreatment identification of the sentinel lymph nodes (SLNs) in gastric cancer patients may have great advantages for minimally invasive treatment. No reliable method for the detection of SLNs during the pretreatment period in gastric cancer has been established. The aim
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