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85549

Sigma-Aldrich

Span® 85

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Synonym(s):
Sorbitan trioleate, Span® 85
Empirical Formula (Hill Notation):
C60H108O8
CAS Number:
Molecular Weight:
957.49
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:

description

non-ionic

refractive index

n20/D 1.476 (lit.)

viscosity

200-300 mPa.s(20 °C)

HLB value

1.8±1.1

density

0.94 g/mL at 20 °C
0.956 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H](CO)[C@H]1OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-52-54(61)59-60(68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)55(53-66-59)67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27+/t54-,55+,59-,60-/m1/s1

InChI key

ZBNRGEMZNWHCGA-WECPCUOASA-N

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Legal Information

Span is a registered trademark of Croda International PLC

replaced by

Product No.
Description
Pricing

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Gülay Büyükköroğlu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 174-183 (2016-10-30)
Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic agent and a genetic material that
Ming-Hsi Huang et al.
PloS one, 5(8), e12279-e12279 (2010-09-03)
Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5N1 whole-virion vaccine
Determination of sorbitan trioleate in metered-dose inhalers by supercritical-fluid chromatography.
M Di Maso et al.
Journal of pharmaceutical and biomedical analysis, 8(3), 303-305 (1990-01-01)
H Todo et al.
International journal of pharmaceutics, 220(1-2), 101-110 (2001-05-30)
The lungs are useful for administration of macromolecules, which are poorly absorbed from the intestine. In the present study, we prepared several dry powder formulations of insulin using a spray drying technique to examine the effect of additives on insulin
Z H Cong et al.
Journal of animal science, 87(3), 1085-1096 (2008-12-23)
The effects of 3 nonionic surfactants (NIS), including alkyl polyglucoside (APG), sorbitan trioleate (Span85), and polyoxyethylene sorbitan monostearate (Tween80), on in vitro fermentation characteristics of maize stover, rice straw, and wheat straw were examined using an in vitro gas production

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