84480
Sanguinarine chloride
≥98.0% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C20H14ClNO4
CAS Number:
Molecular Weight:
367.78
UNSPSC Code:
12352203
Beilstein/REAXYS Number:
3832138
MDL number:
InChI key
GIZKAXHWLRYMLE-UHFFFAOYSA-M
SMILES string
[Cl-].C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14
InChI
1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1
assay
≥98.0% (HPLC)
solubility
methanol: 20 mg/mL, clear, orange
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Irene Bessi et al.
ACS chemical biology, 7(6), 1109-1119 (2012-04-11)
G-quadruplex structures can be formed at the single-stranded overhang of telomeric DNA, and ligands able to stabilize this structure have recently been identified as potential anticancer drugs. Among the potential G-quadruplex binders, we have studied the binding ability of berberine
Xiaofeng Niu et al.
Toxicology and applied pharmacology, 267(3), 256-265 (2013-01-29)
The quaternary ammonium salt, sanguinarine (SANG), is of great practical and research interest because of its pronounced, widespread physiological effects, which promote anti-microbial and anti-inflammatory responses in experimental animals. Although SANG is originally shown to possess anti-inflammatory properties and it
Fei Wu et al.
PloS one, 7(11), e48251-e48251 (2012-11-28)
Small molecules that can specifically bind to a DNA abasic site (AP site) have received much attention due to their importance in DNA lesion identification, drug discovery, and sensor design. Herein, the AP site binding behavior of sanguinarine (SG), a
Xiaofeng Niu et al.
European journal of pharmacology, 689(1-3), 262-269 (2012-06-19)
The quaternary ammonium salt, sanguinarine (SANG), is of great practical and research interest because of its pronounced, widespread physiological effects, which promote anti-microbial and anti-inflammatory responses in experimental animals. Sanguinarine was originally shown to possess anti-inflammatory properties and it has
Priya Weerasinghe et al.
Experimental and molecular pathology, 93(3), 302-308 (2012-10-06)
It is now increasingly accepted that apoptosis may not be the only form of cell death seen in vitro and in vivo; hence there is a need to study novel forms of cell death. The explosion of cell death research
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