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83275

Sigma-Aldrich

4-Pyrrolidinopyridine

purum, ≥98.0% (NT)

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Empirical Formula (Hill Notation):
C9H12N2
CAS Number:
Molecular Weight:
148.20
Beilstein:
472443
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

purum

Quality Level

Assay

≥98.0% (NT)

form

crystals

mp

54-58 °C (lit.)
55-61 °C

solubility

methanol: 0.1 g/mL, clear

SMILES string

C1CCN(C1)c2ccncc2

InChI

1S/C9H12N2/c1-2-8-11(7-1)9-3-5-10-6-4-9/h3-6H,1-2,7-8H2

InChI key

RGUKYNXWOWSRET-UHFFFAOYSA-N

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Other Notes

Hypernucleophilic acylation catalyst. Reviews

Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

233.6 °F

Flash Point(C)

112 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A. Hassner
Tetrahedron, 34, 2069-2069 (1978)
Brian L Hodous et al.
Journal of the American Chemical Society, 124(34), 10006-10007 (2002-08-22)
The first method for the catalytic enantioselective addition of amines (specifically, pyrroles) to ketenes has been developed, and it has been demonstrated that the resulting acylpyrroles can be transformed into a broad spectrum of useful derivatives. On the basis of
Hoefle, G., et al.
Angewandte Chemie (International Edition in English), 90, 602-602 (1978)
H Kai et al.
The Journal of pharmacy and pharmacology, 48(1), 53-56 (1996-01-01)
We have examined the effects of pyridine derivatives on phosphatidylcholine secretion in primary cultures of rat type II pneumocytes. Of 12 pyridine derivatives, 4-aminopyridine, 4-dimethylaminopyridine and 4-pyrolidinopyridine had a stimulatory effect on phosphatidylcholine secretion, whereas other derivatives had little effect.
E.F. Scriven
Chemical Society Reviews, 12, 129-129 (1983)

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