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Merck
CN

81292

Poly(ethylene glycol)

greener alternative

analytical standard, suitable for gel permeation chromatography (GPC), 4,000

Synonym(s):

PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24887743
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

mol wt

Mn ~4120
Mp ~4450
Mw ~4240

greener alternative product characteristics

Safer Solvents and Auxiliaries
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sustainability

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technique(s)

gel permeation chromatography (GPC): suitable

Mw/Mn

~1.03

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

greener alternative category

Aligned

storage temp.

2-8°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) (PEG) is regarded as the gold standard for stealth polymers in polymer based drug delivery. PEGs and their anionic or non-ionic derivatives are widely used in cosmetic products.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

PEG is known to modify enzymes and proteins for the preparation of improved therapeutic agents.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7749
BCCN5204
BCCN4435
BCCN0352
BCCM8111

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Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products.
Fruijtier-Polloth C.
Toxicology, 214(1-2), 1- 38 (2005)
C Woghiren et al.
Bioconjugate chemistry, 4(5), 314-318 (1993-09-01)
Monomethoxypolyethylene glycol (mPEG) of average molecular weight 5000 was transformed in a series of synthetic steps to a new activated form of PEG, a stable thiol-protected intermediary, for reaction with cysteine residues in proteins under mild conditions to produce PEG--protein
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Knop K, et al.
Angewandte Chemie (International Edition in English), 49(36), 6288-6308 (2010)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
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