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80645

Sigma-Aldrich

Piperidine solution

suitable for peptide synthesis, 20% in DMF

Synonym(s):

Azacyclohexane, Cyclopentimine, Hexahydropyridine, Pentamethyleneimine

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About This Item

Empirical Formula (Hill Notation):
C5H11N
CAS Number:
Molecular Weight:
85.15
Beilstein:
1421082
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.31

form

liquid

Quality Level

concentration

20% in DMF

impurities

≤0.1% water

refractive index

n20/D 1.434

density

0.930 g/mL at 20 °C

application(s)

peptide synthesis

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChI key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

Application


  • Targeted potent antimicrobial and antitumor oxygen-heterocyclic-based pyran analogues: synthesis and computational studies.: This research highlights the application of piperidine solution in the synthesis of novel pyran analogues, demonstrating its utility in enhancing antimicrobial and antitumor properties through advanced chemical synthesis and computational modeling techniques (El-Wahab et al., 2024).

  • Heterocyclic Amine-Induced Feeding Deterrence and Antennal Response of Honey Bees.: Utilizing piperidine solution, this study examines the impact of heterocyclic amines on honey bees, providing valuable insights into the chemical ecology of plant-insect interactions and potential strategies for pest control in agriculture (Larson et al., 2021).

  • Effects of Desilication in NaOH/Piperidine Medium and Phosphorus Modification on the Catalytic Activity of HZSM-5 Catalyst in Methanol to Propylene Conversion.: This study uses piperidine solutions to modify the surface properties of HZSM-5 catalysts, significantly enhancing their performance in methanol to propylene conversion processes, highlighting the application in industrial catalysis (Safaei et al., 2021).

  • MWW-Type Titanosilicate Synthesized by Simply Treating ERB-P Zeolite with Acidic H(2)TiF(6) and Its Catalytic Performance in a Liquid Epoxidation of 1-Hexene with H(2)O(2).: This research utilizes piperidine solution in the synthesis of novel titanosilicate materials, exploring its effectiveness in the catalytic epoxidation of hexene, demonstrating the potential of piperidine in facilitating advanced material synthesis (Guo et al., 2020).

Other Notes

Sales restrictions may apply

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Corr. 1B

WGK

WGK 2

Flash Point(F)

82.4 °F

Flash Point(C)

28 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

易制毒化学品(2类)
危险化学品

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Carmine Pasquale Cerrato et al.
Journal of materials chemistry. B, 8(47), 10825-10836 (2020-11-12)
Cell-penetrating peptides are a promising therapeutic strategy for a wide variety of degenerative diseases, ageing, and cancer. Among the multitude of cell-penetrating peptides, PepFect14 has been preferentially used in our laboratory for oligonucleotide delivery into cells and in vivo mouse
Total synthesis of (-)-kopsinine by an asymmetric one-pot [n+2+3] cyclization.
Shingo Harada et al.
Chemistry, an Asian journal, 7(10), 2196-2198 (2012-08-22)
J Phillip Turner et al.
ACS chemical neuroscience, 5(7), 552-558 (2014-04-03)
Alzheimer's disease (AD) is the most common form of dementia and the sixth leading cause of death in the United States. Plaques composed of aggregated amyloid-beta protein (Aβ) accumulate between the neural cells in the brain and are associated with
Niina Aaltonen et al.
Chemistry & biology, 20(3), 379-390 (2013-03-26)
Monoacylglycerol lipase (MAGL) terminates the signaling function of the endocannabinoid, 2-arachidonoylglycerol (2-AG). During 2-AG hydrolysis, MAGL liberates arachidonic acid, feeding the principal substrate for the neuroinflammatory prostaglandins. In cancer cells, MAGL redirects lipid stores toward protumorigenic signaling lipids. Thus MAGL
Xuwang Chen et al.
Bioorganic & medicinal chemistry, 20(12), 3856-3864 (2012-05-18)
A novel series of piperidine-linked amino-triazine derivatives were designed, synthesized and evaluated for in vitro anti-HIV activity as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. Screening results indicated that most compounds showed excellent activity against wild-type

Protocols

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

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