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Bergenin

analytical standard

Synonym(s):

Ardisic acid B, Cuscutin, Vakerin

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About This Item

Empirical Formula (Hill Notation):
C14H16O9
CAS Number:
477-90-7
Molecular Weight:
328.27
MDL number:
MFCD00133120
UNSPSC Code:
85151701
PubChem Substance ID:
329768897
NACRES:
NA.24

grade

analytical standard

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤10.0% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1

InChI key

YWJXCIXBAKGUKZ-HJJNZUOJSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ0626
BCCH4735
BCCH0764
BCCG4411
BCCF8125

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Shuang He et al.
Drug development and industrial pharmacy, 38(10), 1280-1288 (2011-12-31)
A novel coated gastric floating drug-delivery system (GFDDS) of bergenin (BN) and cetirizine dihydrochloride (CET) was developed. First, the pharmacodynamic studies were performed and the results revealed that the new compounds of bergenin/cetirizine dihydrochloride had comparative efficacy as commercial products
Xuan Qin et al.
Arzneimittel-Forschung, 60(4), 198-204 (2010-05-22)
The purpose of this study was to explore the absorption characteristics of bergenin (CAS 477-90-7) and to improve its bioavailability by modulation of the gastrointestinal (GI) absorption using two enhancers (borneol and Poloxamer 188, resp. F68) based on in situ
Yusei Kashima et al.
Journal of oleo science, 62(6), 391-401 (2013-06-04)
Here we evaluated the inhibitory effects of bergenin analogues (2-10), prepared from naturally occurring bergenin, (1) on β-secretase (BACE1) activity. All the bergenin analogues that were analyzed inhibited BACE1 in a dose-dependent manner. 11-O-protocatechuoylbergenin (5) was the most potent inhibitor
Birger Dittrich et al.
Acta crystallographica. Section B, Structural science, 65(Pt 6), 749-756 (2009-11-20)
Bergenin, which has been isolated from a variety of tropical plants, has several pharmacological applications in traditional Asian medicine. Its electron-density distribution was obtained from a room-temperature low-resolution X-ray data set measured with point detection making use of multipole populations
Xuan Qin et al.
Acta pharmacologica Sinica, 31(1), 127-136 (2009-12-08)
To prepare a bergenin-phospholipid complex (BPC) to increase oral bioavailability of the drug. In order to obtain the acceptable BPC, a spherical symmetric design-response surface methodology was used for process optimization. The influence of reaction medium, temperature, drug concentration and
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